Immune cell dysfunction within the tumor microenvironment undermines the control of
cancer progression. NK cells play critical roles in limiting early tumor growth and metastatic …

NK cells play a crucial role in host protection during tumorigenesis. Throughout tumor
development, however, NK cells become progressively dysfunctional through a combination …

NK cells control tumor growth directly through targeted cytotoxic granule release or cytokine
secretion and indirectly by orchestrating anti-tumor immune responses. In this issue of …

Natural killer (NK) cells are crucial to various facets of human immunity and function through
direct cytotoxicity or via orchestration of the broader immune response. NK cells exist across …

NK cells are considered an important component of innate immunity, which is the first line of
defensing against tumors and viral infections in the absence of prior sensitization. NK cells …

Immune cell dysfunction within the tumor microenvironment (TME) undermines the control of
cancer progression. Established tumors contain phenotypically distinct, tumor-specific …

The functional impairment of natural killer (NK) cells has been frequently reported in cancer
studies. As one of the central components of host anti-tumor immunity, NK cells exert cellular …

Natural killer (NK) cells are cytotoxic innate lymphocytes that protect against viral infection
and tumor metastasis. Despite their inherent ability to kill a broad range of virally infected …

Natural killer (NK) cells are a population of innate lymphoid cells playing a pivotal role in
host immune responses against infection and tumor growth. These cells have a powerful …

NK cells contribute to protective antitumor immunity, but little is known about the functional
states of NK cells in human solid tumors. To address this issue, we performed single-cell …