The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

M Jain, HE Olsen, B Paten, M Akeson - Genome biology, 2016 - Springer
Nanopore DNA strand sequencing has emerged as a competitive, portable technology.
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …

Nanopore sequencing in blood diseases: a wide range of opportunities

CF Minervini, C Cumbo, P Orsini, L Anelli… - Frontiers in …, 2020 - frontiersin.org
The molecular pathogenesis of hematological diseases is often driven by genetic and
epigenetic alterations. Next-generation sequencing has considerably increased our …

Application of nanopore sequencing in the detection of foodborne microorganisms

Y Zhou, M Ren, P Zhang, D Jiang, X Yao, Y Luo… - Nanomaterials, 2022 - mdpi.com
Foodborne pathogens have become the subject of intense interest because of their high
incidence and mortality worldwide. In the past few decades, people have developed many …

Rapid detection of single nucleotide polymorphisms using the MinION nanopore sequencer: a feasibility study for perioperative precision medicine

Y Tabata, Y Matsuo, Y Fujii, A Ohta, K Hirota - JA Clinical Reports, 2022 - Springer
Introduction Precision medicine is a phrase used to describe personalized medical care
tailored to specific patients based on their clinical presentation and genetic makeup …

Nano2NGS-Muta: a framework for converting nanopore sequencing data to NGS-liked sequencing data for hotspot mutation detection

J Lang, J Sun, Z Yang, L He, Y He… - NAR Genomics and …, 2022 - academic.oup.com
Nanopore sequencing, also known as single-molecule real-time sequencing, is a third/fourth
generation sequencing technology that enables deciphering single DNA/RNA molecules …

Integrated sample cleanup and capillary array electrophoresis microchip for forensic short tandem repeat analysis

P Liu, JR Scherer, SA Greenspoon, TN Chiesl… - Forensic science …, 2011 - Elsevier
A twelve-lane capillary array electrophoresis (CAE) microsystem is developed that utilizes
an efficient inline capture injection process together with the classical radial microfabricated …

Bioinformatics of nanopore sequencing

W Makałowski, V Shabardina - Journal of human genetics, 2020 - nature.com
Nanopore sequencing is one of the most exciting new technologies that undergo dynamic
development. With its development, a growing number of analytical tools are becoming …

Application of nanopore sequencing technology in the clinical diagnosis of infectious diseases

LL Zhang, C Zhang, JP Peng - Biomedical and Environmental Sciences, 2022 - Elsevier
Infectious diseases are an enormous public health burden and a growing threat to human
health worldwide. Emerging or classic recurrent pathogens, or pathogens with resistant …

Accurate detection of single nucleotide polymorphisms using nanopore sequencing

E Rocío, Z Nikola, DM Adele, R Yannick - bioRxiv, 2020 - biorxiv.org
Background Nanopore sequencing is a powerful single molecule DNA sequencing
technology which provides a high throughput and long sequence reads. Nevertheless, its …

Nanopore-based sensing devices and applications to genome sequencing: a brief history and the missing pieces

S Huang - Chinese science bulletin, 2014 - Springer
A nanopore on an impermeable membrane, which separates two chambers containing
electrolytic solution, can be used as a nanometre-sized Coulter counter for single-molecule …