Nitric oxide in renal health and disease

BC Kone - American journal of kidney diseases, 1997 - Elsevier
Nitrix oxide (NO) is a labile radical gas that is widely acclaimed as one of the most important
molecules in biology. Through covalent modifications of target proteins and redox reactions …

Nitric oxide synthesis in the kidney: isoforms, biosynthesis, and functions in health

BC Kone - Seminars in nephrology, 2004 - Elsevier
Nitric oxide (NO) is a gaseous free radical that serves cell signaling, cellular energetics, host
defense, and inflammatory functions in virtually all cells. In the kidney and vasculature, NO …

Role of nitric oxide in inflammatory conditions

RC Blantz, K Munger - Nephron, 2002 - karger.com
Nitric oxide (NO) plays an important regulatory/modulatory role in a variety of inflammatory
conditions. NO is a small, short-lived molecule that is released from a variety of cells in …

Nitric oxide in the normal kidney and in patients with diabetic nephropathy

P Tessari - Journal of nephrology, 2015 - Springer
Nitric oxide (NO) is a gas with biological and regulatory properties, produced from arginine
by the way of nitric oxide synthases (NOS), and with a very short half-life (few seconds). A …

Biosynthesis and homeostatic roles of nitric oxide in the normal kidney

BC Kone, C Baylis - American Journal of Physiology-Renal …, 1997 - journals.physiology.org
Nitric oxide (NO) is an important molecular mediator of numerous physiological processes in
virtually every organ. In the kidney, NO plays prominent roles in the homeostatic regulation …

Nitric oxide and the kidney

SP Sharma - Indian Journal of Nephrology, 2004 - journals.lww.com
Recent years have witnessed a phenomenal scientific interest in the vascular biology,
particularly the relevance of nitric oxide (NO) in cardiovascular and renal physiology and …

Nitric oxide signalling in kidney regulation and cardiometabolic health

M Carlström - Nature reviews nephrology, 2021 - nature.com
The prevalence of cardiovascular and metabolic disease coupled with kidney dysfunction is
increasing worldwide. This triad of disorders is associated with considerable morbidity and …

Nitric oxide in the kidney: synthesis, localization, and function

S Bachmann, P Mundel - American Journal of Kidney Diseases, 1994 - Elsevier
The characterization and cloning of constitutive and inducible nitric oxide (NO)-synthesizing
enzymes and the development of specific inhibitors of the L-arginine NO pathway have …

Glomerular actions of nitric oxide.

L Raij, C Baylis - Kidney international, 1995 - europepmc.org
NO, a simple molecule synthesized from L-arginine by NO synthases, has been identified to
play an important role in cell communication, cell defense and cell injury. The half life of NO …

Physiology and pathophysiology of nitric oxide in chronic renal disease

M Noris, G Remuzzi - Proceedings of the Association of …, 1999 - Wiley Online Library
Nitric oxide (NO), an L‐arginine derivative, exerts a variety of renal and extrarenal
physiological and pathophysiological effects. NO is generated by three isoforms of nitric …