Demethoxycurcumin mediated targeting of MnSOD leading to activation of apoptotic pathway and inhibition of Akt/NF-κB survival signalling in human glioma U87 MG …
Earlier, we reported that Demethoxycurcumin (DMC) suppressed the growth of human
glioma U87 MG cells by downregulation of Bcl-2 expression. In the present work, we …
glioma U87 MG cells by downregulation of Bcl-2 expression. In the present work, we …
Demethoxycurcumin retards cell growth and induces apoptosis in human brain malignant glioma GBM 8401 cells
TY Huang, CW Hsu, WC Chang… - Evidence‐Based …, 2012 - Wiley Online Library
Demethoxycurcumin (DMC; a curcumin‐related demethoxy compound) has been recently
shown to display antioxidant and antitumor activities. It has also produced a potent …
shown to display antioxidant and antitumor activities. It has also produced a potent …
Proteasome mediated degradation of CDC25C and Cyclin B1 in Demethoxycurcumin treated human glioma U87 MG cells to trigger G2/M cell cycle arrest
Recently, we have reported that Demethoxycurcumin induced Reactive oxygen species via
inhibition of Mitochondrial Superoxide Dismutase is an initial event to trigger apoptosis …
inhibition of Mitochondrial Superoxide Dismutase is an initial event to trigger apoptosis …
Bisdemethoxycurcumin Induces Cell Apoptosis and Inhibits Human Brain Glioblastoma GBM 8401/Luc2 Cell Xenograft Tumor in Subcutaneous Nude Mice In Vivo
TC Hsia, SF Peng, FS Chueh, KW Lu, JL Yang… - International Journal of …, 2022 - mdpi.com
Bisdemethoxycurcumin (BDMC) has biological activities, including anticancer effects in vitro;
however, its anticancer effects in human glioblastoma (GBM) cells have not been examined …
however, its anticancer effects in human glioblastoma (GBM) cells have not been examined …
Demethoxycurcumin suppresses proliferation, migration, and invasion of human brain glioblastoma multiforme GBM 8401 cells via PI3K/Akt pathway
RY Su, SC Hsueh, CY Chen, MJ Hsu, HF Lu… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Demethoxycurcumin (DMC), one of the derivatives of curcumin, has been
shown to induce apoptotic cell death in many human cancer cell lines. However, there is no …
shown to induce apoptotic cell death in many human cancer cell lines. However, there is no …
Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme GBM 8401 cell migration and invasion via affecting NF‐κB and MMP‐2 and MMP‐9 …
CJ Chen, HS Shang, YL Huang, N Tien… - Environmental …, 2022 - Wiley Online Library
Human glioblastoma (GBM) is one of the common cancer death in adults worldwide, and its
metastasis will lead to difficult treatment. Finding compounds for future to develop treatment …
metastasis will lead to difficult treatment. Finding compounds for future to develop treatment …
[HTML][HTML] Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells
Y Wu, P Zhang, H Yang, Y Ge… - Molecular Medicine …, 2017 - spandidos-publications.com
The present study investigated the effects and mechanisms of demethoxycurcumin (DMC)
on a human skin squamous cell carcinoma cell line, A431, and a human keratinocyte cell …
on a human skin squamous cell carcinoma cell line, A431, and a human keratinocyte cell …
Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells
M Ramkumar, S Rajasankar, VV Gobi… - … and alternative medicine, 2017 - Springer
Background Mitochondrial dysfunction and oxidative stress are the main toxic events
leading to dopaminergic neuronal death in Parkinson's disease (PD) and identified as vital …
leading to dopaminergic neuronal death in Parkinson's disease (PD) and identified as vital …
Dimethoxycurcumin-induced cell death in human breast carcinoma MCF7 cells: evidence for pro-oxidant activity, mitochondrial dysfunction, and apoptosis
A Kunwar, S Jayakumar, AK Srivastava… - Archives of …, 2012 - Springer
The factors responsible for the induction of cell death by dimethoxycurcumin (Dimc), a
synthetic analog of curcumin, were assessed in human breast carcinoma MCF7 cells. Initial …
synthetic analog of curcumin, were assessed in human breast carcinoma MCF7 cells. Initial …
The anti-cancer effect of four curcumin analogues on human glioma cells
SM Luo, YP Wu, LC Huang, SM Huang… - OncoTargets and …, 2021 - Taylor & Francis
Purpose Glioblastoma multiforme (GBM) is the primary aggressive malignancy of the brain
with poor outcome. Curcumin analogues are polyphenolic compounds as the bioactive …
with poor outcome. Curcumin analogues are polyphenolic compounds as the bioactive …