Hormesis effects of silver nanoparticles at non-cytotoxic doses to human hepatoma cells

ZH Jiao, M Li, YX Feng, JC Shi, J Zhang, B Shao - PloS one, 2014 - journals.plos.org
Silver nanoparticles (AgNPs) have attracted considerable attentions due to their unique
properties and diverse applications. Although it has been reported that AgNPs have acute …

Adaptation of HepG2 cells to silver nanoparticles-induced stress is based on the pro-proliferative and anti-apoptotic changes in gene expression

K Brzóska, S Męczyńska-Wielgosz… - …, 2015 - academic.oup.com
Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials due to their
antibacterial properties. Owing to the recent boost in the usage of AgNPs-containing …

Comparative proteomic analysis reveals the different hepatotoxic mechanisms of human hepatocytes exposed to silver nanoparticles

TY Wong, N Yan, KKL Kwan, Y Pan, J Liu… - Journal of Hazardous …, 2023 - Elsevier
Silver nanoparticles (AgNPs), which have been used extensively in consuming products and
eventually released into the natural environment, have aroused concerns recently because …

p38 MAPK activation, DNA damage, cell cycle arrest and apoptosis as mechanisms of toxicity of silver nanoparticles in Jurkat T cells

HJ Eom, J Choi - Environmental science & technology, 2010 - ACS Publications
To identify potential harmful effects of silver nanoparticles (AgNPs) on human health, a
comprehensive toxicity assay was conducted on human Jurkat T cells, using oxidative stress …

Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells

S Kim, JE Choi, J Choi, KH Chung, K Park, J Yi… - Toxicology in vitro, 2009 - Elsevier
Cytotoxicity induced by silver nanoparticles (AgNPs) and the role that oxidative stress plays
in this process were demonstrated in human hepatoma cells. Toxicity induced by silver …

Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media

Y Xue, T Zhang, B Zhang, F Gong… - Journal of Applied …, 2016 - Wiley Online Library
Abstract Silver nanoparticles (Ag NPs) have been widely used in medical and healthcare
products owing to their unique antibacterial activities. However, their safety for humans and …

Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis

MJ Piao, KA Kang, IK Lee, HS Kim, S Kim, JY Choi… - Toxicology letters, 2011 - Elsevier
Silver nanoparticles (AgNPs), which have well-known antimicrobial properties, are
extensively used in various medical and general applications. Despite the widespread use …

Comparison of in vitro toxicity of silver ions and silver nanoparticles on human hepatoma cells

IV Vrček, I Žuntar, R Petlevski, I Pavičić… - Environmental …, 2016 - Wiley Online Library
Scientific information on the potential harmful effects of silver nanoparticles (AgNPs) on
human health severely lags behind their exponentially growing applications in consumer …

In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells

K Kawata, M Osawa, S Okabe - Environmental science & …, 2009 - ACS Publications
Although it has been reported that silver nanoparticles (Ag-NPs) have strong acute toxic
effects to various cultured cells, the toxic effects at noncytotoxic doses are still unknown. We …

Effects of Silver Nanoparticles on the Liver and Hepatocytes In Vitro

BK Gaiser, S Hirn, A Kermanizadeh… - Toxicological …, 2013 - academic.oup.com
With the increasing use and incorporation of nanoparticles (NPs) into consumer products,
screening for potential toxicity is necessary to ensure customer safety. NPs have been …