Echo-time dependence of the BOLD response transients–a window into brain functional physiology

M Havlicek, D Ivanov, BA Poser, K Uludag - Neuroimage, 2017 - Elsevier
The blood oxygenation level-dependent (BOLD) fMRI response to neuronal activation
results from a complex interplay of induced metabolic and vascular changes. Thus, its …

Temporal jitter of the BOLD signal reveals a reliable initial dip and improved spatial resolution

M Watanabe, A Bartels, JH Macke, Y Murayama… - Current Biology, 2013 - cell.com
Summary fMRI, one of the most important noninvasive brain imaging methods, relies on the
blood oxygen level-dependent (BOLD) signal, whose precise underpinnings are still not fully …

Spatial heterogeneity of the nonlinear dynamics in the FMRI BOLD response

RM Birn, ZS Saad, PA Bandettini - Neuroimage, 2001 - Elsevier
Recent studies of blood oxygenation level dependent (BOLD) signal responses averaged
over a region of interest have demonstrated that the response is nonlinear with respect to …

Relative latency and temporal variability of hemodynamic responses at the human primary visual cortex

FH Lin, JR Polimeni, JFL Lin, KWK Tsai, YH Chu… - Neuroimage, 2018 - Elsevier
The blood-oxygen-level-dependent (BOLD) functional MRI (fMRI) signal is a robust
surrogate for local neuronal activity. However, it has been shown to vary substantially across …

Transient and sustained BOLD responses to sustained visual stimulation

K Uludağ - Magnetic resonance imaging, 2008 - Elsevier
Examining the transients of the blood-oxygenation-level-dependent (BOLD) signal using
functional magnetic resonance imaging is a tool to probe basic brain physiology. In addition …

The effect of stimulus duty cycle and “off” duration on BOLD response linearity

RM Birn, PA Bandettini - Neuroimage, 2005 - Elsevier
An ongoing question in functional MRI is precisely how measured signal changes relate to
neuronal activity. While this question has been probed using animal models and …

Hemodynamic nonlinearities affect BOLD fMRI response timing and amplitude

JA de Zwart, P van Gelderen, JM Jansma, M Fukunaga… - Neuroimage, 2009 - Elsevier
The interpretation of functional magnetic resonance imaging (fMRI) studies based on blood
oxygen-level dependent (BOLD) contrast generally relies on the assumption of a linear …

Dynamics of the cerebral blood flow response to brief neural activity in human visual cortex

JH Kim, AJ Taylor, DJJ Wang… - Journal of Cerebral …, 2020 - journals.sagepub.com
The blood oxygen-level dependent (BOLD) functional magnetic resonance imaging (fMRI)
signal depends on an interplay of cerebral blood flow (CBF), oxygen metabolism, and …

Variability of the coupling of blood flow and oxygen metabolism responses in the brain: a problem for interpreting BOLD studies but potentially a new window on the …

RB Buxton, VEM Griffeth, AB Simon… - Frontiers in …, 2014 - frontiersin.org
Recent studies from our group and others using quantitative fMRI methods have found that
variations of the coupling ratio of blood flow (CBF) and oxygen metabolism (CMRO2) …

Stimulus-dependent BOLD and perfusion dynamics in human V1

RD Hoge, J Atkinson, B Gill, GR Crelier, S Marrett… - Neuroimage, 1999 - Elsevier
Blood oxygenation level-dependent (BOLD) fMRI signals often exhibit pronounced over-or
undershoot upon changes in stimulation state. Current models postulate that this is due to …