Traditional medicine has been a fertile source for revealing novel lead molecules for modern
drug discovery. In plants, terpenoids represent a chemical defense against environmental …

Natural products play a significant role in human health in relation to the prevention and
treatment of inflammatory conditions. Among them, terpenoids (also referred to as terpenes) …

Nuclear factor-κB (NF-κB) is a transcription factor that is activated in response to various
inflammatory stimuli such as cytokines, growth factors, hormones, mitogens, carcinogens …

Extensive research within the last two decades revealed that most chronic illnesses,
including cancer, neurological, autoimmune and cardiovascular diseases are mediated …

Cancer is a multifactorial heterogeneous disease characterized by multistage nature of
pathogenesis. Over the past two or three decades, we have witnessed an enormous …

Nuclear factor κB (NF-κB) is a ubiquitous regulator of the signalome and is indispensable for
various biological cell functions. NF-κB consists of five transcription factors that execute both …

A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

Natural products are mainly secondary metabolites produced by plants, microorganisms,
and animals, which are still abundant in modern drug discovery. Terpenoids are the most …

NF-κB is a ubiquitous and well-characterised protein responsible for the regulation of
complex phenomena, with a pivotal role in controlling cell signalling in the body under …

Polyphenol compounds are natural antioxidants, which are rich in anti-inflammatory and
antioxidant components. They have a wide range of medicinal benefits that are believed to …