[HTML][HTML] Immunologic features in coronavirus disease 2019: functional exhaustion of T cells and cytokine storm

S Mahmoudi, M Rezaei, N Mansouri, M Marjani… - Journal of clinical …, 2020 - Springer
To the Editor: Since the emergence of Coronavirus Disease 2019 (COVID-19) caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, the …

The deregulated immune reaction and cytokines release storm (CRS) in COVID-19 disease

R Pasrija, M Naime - International Immunopharmacology, 2021 - Elsevier
COVID-19 caused by the SARS-CoV-2 virus, accompanies an unprecedented spike in
cytokines levels termed cytokines release syndrome (CRS), in critically ill patients. Clinicians …

[HTML][HTML] Overview of the pathogenesis of COVID‑19

C Li, Q He, H Qian, J Liu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
At present, the pathogenesis of the novel coronavirus disease 2019 (COVID‑19) has not
been fully elucidated. Clinical and experimental findings from studies investigating COVID …

[HTML][HTML] Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

[HTML][HTML] Coronavirus disease-2019 (COVID-19): an updated review

M Rudrapal, SJ Khairnar, LB Borse… - Drug research, 2020 - thieme-connect.com
The current outbreak of novel Coronavirus Disease-2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major pandemic situation and …

[PDF][PDF] Cytokine-targeted therapy in severely ill COVID-19 patients: options and cautions

M Rahmati, MA Moosavi - mortality, 2020 - researchgate.net
Dear Editor, Coronavirus disease 2019 (COVID-19) is an infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) with the symptoms …

Inflammatory pathways in COVID‐19: Mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Coronavirus disease-2019: A review on the disease exacerbation via cytokine storm and concurrent management

H Sunkara, SMR Dewan - International immunopharmacology, 2021 - Elsevier
Abstract Setting up treatment strategies is the highest concern today to reduce the fatality of
COVID-19. Due to a very new kind of virus attack, no specific treatment has been discovered …

[HTML][HTML] Novel coronavirus: current understanding of clinical features, diagnosis, pathogenesis, and treatment options

MR Mungroo, NA Khan, R Siddiqui - Pathogens, 2020 - mdpi.com
Since December 2019, coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in devastating …

[HTML][HTML] Pathological findings in COVID-19 as a tool to define SARS-CoV-2 pathogenesis. A systematic review

C Mondello, S Roccuzzo, O Malfa… - Frontiers in …, 2021 - frontiersin.org
Introduction: The World Health Organization declared the COVID-19 pandemic in March
2020. COVID-19 still represents a worldwide health emergency, which causesa severe …