Evolving concepts in the pathophysiology of atherosclerosis: From endothelial dysfunction to thrombus formation through multiple shades of inflammation

G Cimmino, S Muscoli, S De Rosa… - Journal of …, 2023 - journals.lww.com
Atherosclerosis is the anatomo-pathological substrate of most cardio, cerebro and vascular
diseases such as acute and chronic coronary syndromes, stroke and peripheral artery …

A focus on inflammation as a major risk factor for atherosclerotic cardiovascular diseases

I Gregersen, S Holm, TB Dahl… - Expert review of …, 2016 - Taylor & Francis
Atherosclerosis is a dynamic, pathogenic process in the artery wall, with potential adverse
outcome for the host. Acute events such as myocardial infarction and ischemic stroke often …

[PDF][PDF] Inflammation and thrombosis in coronary atherosclerosis: Pathophysiologic mechanisms and clinical correlations

JA Ambrose, AS Bhullar - EMJ, 2019 - emjreviews.com
Inflammation and thrombosis are interrelated processes that are important in the
pathogenesis of atherothrombosis. Inflammation is important in both the early and late …

Role of gut microbiota in atherosclerosis

AL Jonsson, F Bäckhed - Nature Reviews Cardiology, 2017 - nature.com
Infections have been linked to the development of cardiovascular disease and
atherosclerosis. Findings from the past decade have identified microbial ecosystems …

Mutual interplay of host immune system and gut microbiota in the immunopathology of atherosclerosis

CF Yeh, YH Chen, SF Liu, HL Kao, MS Wu… - International journal of …, 2020 - mdpi.com
Inflammation is the key for the initiation and progression of atherosclerosis. Accumulating
evidence has revealed that an altered gut microbiome (dysbiosis) triggers both local and …

Inflammation and atherosclerosis—revisited

S Pant, A Deshmukh, GS GuruMurthy… - Journal of …, 2014 - journals.sagepub.com
Atherogenesis has been traditionally viewed as a metabolic disease representing arterial
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …

Links between inflammation and thrombogenicity in atherosclerosis

JF Viles-Gonzalez, V Fuster… - Current molecular …, 2006 - ingentaconnect.com
Plaque disruption and subsequent thrombus formation play a critical role in the clinical
manifestations of atherothrombosis. Vulnerable lesions are characterized by the existence of …

Inflammation in atherosclerosis: a cause or a result of vascular disorders?

I Manduteanu, M Simionescu - Journal of cellular and …, 2012 - Wiley Online Library
Sound data support the concept that in atherosclerosis, inflammation and dyslipidemia
intersect each other and that irrespective of the initiator, both participate from the early …

Inflammatory mechanisms in atherosclerosis

I Gregersen, B Halvorsen - Rijeka: IntechOpen, 2018 - books.google.com
Atherosclerosis is a disease of chronic inflammation, characterized by a dysfunctional
interplay between the immune apparatus and lipids. Immune cells, as well as nonimmune …

Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …