Purpose. Oxidative stress induced by reduced blood circulation is a critical pathological
damage to retinal ganglion cells (RGCs) in glaucoma. We previously showed that green tea …

Current clinical treatments have not yet effectively cured progressive retinal ganglion cell
(RGC) death and axonal degeneration after optic nerve (ON) injury. We previously …

Retinal ischemia/reperfusion (IR) injury causes profound tissue damage, especially retinal
ganglion cell death. The aims of the study were twofold:(1) to investigate the benefits of …

Glaucoma is a progressive neuropathy characterized by the loss of retinal ganglion cells
(RGCs). Strategies that delay or halt RGC loss have been recognized as potentially …

Background Resveratrol (RES) is a natural polyphenol that has been shown to protect
retinal ganglion cells (RGCs) following retinal ischemia reperfusion (I/R) injury. However, the …

Green tea extracts exhibit anti-oxidative and anti-inflammatory actions in different disease
conditions. We hypothesized that green tea extract and its catechin constituents ameliorate …

Purpose: Resveratrol has been shown to enhance the survival of retinal ganglion cells
(RGCs) following ischemia-reperfusion (I/R) injury for glaucoma. However, the precise …

Purpose To determine whether water-dispersible hesperetin (WD-Hpt) can prevent
degeneration of ganglion cell neurons in the ischemic retina. Methods Ischemia reperfusion …

The aim of this study was to examine whether the antioxidant epigallocatechin gallate
(EGCG), a catechin-base flavonoid derived from green tea protects retina neurones in situ …

Inflammation is in a wide spectrum of retinal diseases, causing irreversible blindness and
visual impairment. We have previously demonstrated that Green Tea Extract (GTE) is a …