Treating COVID-19: are we missing out the window of opportunity?

J Sundararaj Stanleyraj, N Sethuraman… - Journal of …, 2021 - academic.oup.com
Severe COVID-19 is a biphasic illness, with an initial viral replication phase, followed by a
cascade of inflammatory events. Progression to severe disease is predominantly a function …

COVID-19 therapeutics

D Focosi, M Franchini, F Maggi… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Since the emergence of COVID-19 in 2020, an unprecedented range of therapeutic options
has been studied and deployed. Healthcare providers have multiple treatment approaches …

Union is strength: antiviral and anti-inflammatory drugs for COVID-19

JJ Naveja, A Madariaga-Mazon, F Flores-Murrieta… - Drug discovery today, 2021 - Elsevier
The COVID-19 outbreak has quickly reached pandemic dimensions because of fast human-
to-human transmission. The first reports of the disease date from December 2019 in Wuhan …

[HTML][HTML] Antiviral agents for the treatment of COVID-19: Progress and challenges

M Singh, E de Wit - Cell Reports Medicine, 2022 - cell.com
The COVID-19 pandemic has seen clinical development and use of antiviral therapies at an
unprecedented speed. Antiviral therapies have greatly improved the clinical outcome in …

Emerging pharmacotherapy for COVID-19

B Lipworth, CRW Kuo, R Chan - Journal of the Royal College …, 2020 - journals.sagepub.com
Broadly speaking, pharmacological treatments for COVID-19 can be divided into those
acting on upstream pathways early on in the disease process via suppression of viral …

[HTML][HTML] Urgent needs to accelerate the race for COVID-19 therapeutics

C Batista, S Shoham, O Ergonul, P Hotez… - …, 2021 - thelancet.com
On December 8, 2020, a 91-year-old woman made history as the first person to receive the
COVID-19 vaccine in the United Kingdom. Worldwide vaccination coverage will take time …

The course of mild and moderate COVID-19 infections—the unexpected long-lasting challenge

L Xia, J Chen, T Friedemann, Z Yang… - Open Forum …, 2020 - academic.oup.com
Background The course of disease in mild and moderate COVID-19 has many implications
for mobile patients, such as the risk of spread of the infection, precautions taken, and …

Coronavirus disease 2019 treatment: a review of early and emerging options

EK McCreary, JM Pogue - Open forum infectious diseases, 2020 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus
disease 2019 (COVID-19), has spread across the globe resulting in a pandemic. At the time …

[HTML][HTML] Treatment options for COVID-19: a review

MJ Ali, M Hanif, MA Haider, MU Ahmed… - Frontiers in …, 2020 - frontiersin.org
Background: The recent COVID-19 pandemic sweeping the globe has caused great concern
worldwide. Due to the limited evidence available on the dynamics of the virus and effective …

[HTML][HTML] Scientific evidence in the COVID-19 treatment: A comprehensive review

G Iturricastillo, EÁ Pérez-Urría, F Couñago… - World Journal of …, 2021 - ncbi.nlm.nih.gov
In December 2019, cases of unknown origin pneumonia appeared in Wuhan, China; the
causal agent of this pneumonia was a new virus of the coronaviridae family called severe …