Renal diseases pose significant challenges to global health. With conditions like chronic
kidney disease (CKD) on the rise, there is an urgent need for deeper insights into their …

Despiteimprovedclinicalcareinpatientswithd…, diabetic complications remain a major
healthcare burden. The management of cardiovascular risk factors, such as hyperlipidemia …

Despite recent efforts to increase diversity in genome-wide association studies (GWASs),
most loci currently associated with kidney function are still limited to European ancestry due …

Genome-wide association studies have identified> 50 common variants associated with
kidney function, but these variants do not fully explain the variation in eGFR. We performed a …

Aims/hypothesis Diabetic kidney disease (DKD) is the leading cause of kidney failure and
has a substantial genetic component. Our aim was to identify novel genetic factors and …

Background: Chronic kidney disease (CKD), a major public health burden, is characterised
by a progressive loss of nephron function which leads to an impaired ability to filter the …

Background: Diabetes is the most common cause of end-stage renal disease (ESRD)
worldwide. Diabetic Kidney Disease (DKD) is defined by reduced kidney function and/or …

Many common genetic variants identified by genome-wide association studies for complex
traits map to genes previously linked to rare inherited Mendelian disorders. A systematic …

Chronic kidney disease (CKD) affects~ 10% of the global population, with considerable
ethnic differences in prevalence and aetiology. We assemble genome-wide association …

Genome-wide association studies (GWASs) have advanced our understanding of the
genetic basis for common renal diseases, including chronic kidney disease (CKD) and …