Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …

In natural infection, the survival of Trypanosoma cruzi, despite the complex immune
response elicited including several humoral and cellular components of innate and acquired …

The pathology of Chagas disease presents a complicated and diverse picture in humans.
The major complications and destructive evolutionary outcomes of chronic infection by …

Chagas disease, or American trypanosomiasis, which is caused by the protozoan parasite
Trypanosoma cruzi, is primarily a vector disease endemic in 21 Latin American countries …

Trypanosoma cruzi is the etiologic agent of Chagas' disease, a major health problem in
Latin America and an emerging infectious disease in the United States. Previously, we …

CD8+ T cells are crucial to the control of Trypanosoma cruzi infection and probably act via
multiple mechanisms, the most important being the production of interferon‐γ (IFN‐γ). In the …

MHC‐restricted CD8+ T cells are important during infection with the intracellular protozoan
parasite Trypanosoma cruzi, the causative agent of Chagas disease. Experimental studies …

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi is one of the most
important neglected parasitic diseases in the Americas. Vaccines represent an attractive …

Chagas disease is major public health problem, affecting nearly 10 million people,
characterized by cardiac alterations leading to congestive heart failure and death of 20-40 …

Chagas' disease is caused by Trypanosoma cruzi (T. cruzi) which was once prevalent in
Central and South America. Although the recent success in Triatoma vector control has …