Bacteria produce d-amino acids for incorporation into the peptidoglycan and certain
nonribosomally produced peptides. However, d-amino acids are toxic if mischarged on …

Misincorporation of d-tyrosine (d-Tyr) into cellular proteins due to mischarging of tRNATyr
with d-Tyr by tyrosyl-tRNA synthetase inhibits growth and biofilm formation of Bacillus …

Genetically engineered microbes are of high practical importance due to their cost-effective
production of valuable metabolites and enzymes, and the search for new selectable markers …

The Bacillus subtilis tyrS gene is a member of a group of gram-positive aminoacyl-tRNA
synthetase and amino acid biosynthesis genes which are regulated by transcription …

In this review, we summarize progress on the regulation of the aminoacyl-tRNA synthetase
genes in Bacillus subtilis. Most of the genes encoding this set enzymes in B subtilis are …

The Gram-positive model bacterium Bacillus subtilis can use several amino acids as
sources of carbon and nitrogen. However, some amino acids inhibit the growth of this …

The formation of additional tRNA isoacceptors has been observed in Escherichia coli
growing under conditions of unbalanced growth [lS]. In Bacillus subtilis important changes in …

A spontaneous mutant of Bacillus subtilis resistant to (L)-azetidin-2-carboxylic acid, a
structural analogue of (L)-proline, has been isolated and characterized. Data have been …

Inhibition of microbial growth has often been used as a probe to study the biochemical
genetics of autotrophic (Rittenberg, 1969) and heterotrophic (see Ingram & Jensen, 1973) …

d-Tyr-tRNA Tyr deacylase cleaves the ester bond between a tRNA molecule and a d-amino
acid. In Escherichia coli, inactivation of the gene (dtd) encoding this deacylase increases the …