Complex biological systems are organized across various spatiotemporal scales with
particular scientific disciplines dedicated to the study of each scale (eg genetics, molecular …

Functionally related brain regions are selectively vulnerable to Alzheimer's disease
pathophysiology. However, molecular markers of this pathophysiology (ie, beta-amyloid and …

Here, we report proteomic analyses of 129 human cortical tissues to define changes
associated with the asymptomatic and symptomatic stages of Alzheimer's disease (AD) …

Much effort in recent years has focused on understanding the effects of Alzheimer's disease
(AD) on neural function. This effort has resulted in an enormous number of papers …

The increasing prevalence of Alzheimer's disease (AD) emphasizes the need for sensitive
biomarkers. Memory, a core deficit in AD, involves the interaction of distributed brain …

Alzheimer's disease (AD) is a progressive, neurodegenerative disease that can be clinically
characterized by impaired memory and many other cognitive functions. Previous studies …

Studies have demonstrated that the clinical manifestations of Alzheimer's disease (AD) are
associated with abnormal connections in either functional connectivity networks (FCNs) or …

Background Alzheimer's disease (AD) and behavioral variant frontotemporal dementia
(bvFTD) cause distinct atrophy and functional disruptions within two major intrinsic brain …

While resting state functional connectivity has been shown to decrease in patients with mild
and/or moderate Alzheimer's disease, it is not yet known how functional connectivity …

Findings derived from neuroimaging of the structural and functional organization of the
human brain have led to the widely supported hypothesis that neuronal networks of …