Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
COVID-19, a disease that involves significant lung tissue damage. How SARS-CoV-2 …

Summary SARS-CoV-2, the causative agent of the present COVID-19 pandemic, possesses
eleven accessory proteins encoded in its genome, and some have been implicated in …

Many patients with severe COVID-19 suffer from pneumonia and the elucidation of the
mechanisms underlying the development of this severe condition is important. The in vivo …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths, posing a substantial threat to global public health. Viruses evolve different strategies …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes six accessory
proteins (3a, 6, 7a, 7b, 8, and 9b) for which limited information is available on their role in …

Abstract Background SARS-CoV-2 causes COVID-19 which has a widely diverse disease
profile. The mechanisms underlying its pathogenicity remain unclear. We set out to identify …

Current therapeutic strategies and vaccines against SARS-CoV-2 are mainly focused on the
Spike protein despite there are other viral proteins with important roles in COVID-19 …

Therapeutic inhibition of critical viral functions is important for curtailing coronavirus disease
2019 (COVID-19). We sought to identify antiviral targets through the genome-wide …

SARS-CoV-2 is the causative agent of a new type of coronavirus infection, COVID-19, which
has rapidly spread worldwide. The overall genome sequence homology between SARS …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome contains nine
open reading frames (ORFs) that encode for accessory proteins which, although …