Astrocytes are the most abundant glial cells in the central nervous system (CNS) mediating a
variety of homeostatic functions, such as spatial K+ buffering or neurotransmitter reuptake. In …

We have previously demonstrated that human astrocytes are GABAergic cells. Throughout
the adult human brain, they express the GABA synthesizing enzyme GAD 67, the GABA …

Astrocytes, the most numerous glial cells in the brain, play an important role in preserving
normal neural functions and mediating the pathogenesis of neurological disorders. Recent …

Gamma-amino butyric acid (GABA) is the major inhibitory neurotransmitter that is known to
be synthesized and released from GABAergic neurons in the brain. However, recent studies …

GABA (gamma-aminobutyric acid) is considered to be the major inhibitory neurotransmitter
that is synthesized in and released from GABA-ergic neurons in the brain. However, recent …

Synaptic regulation of the primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) is
essential for brain function. Cerebral GABA homeostasis is tightly regulated through multiple …

GABA is the main inhibitory neurotransmitter in the mammalian brain, and perturbed GABA
signalling is the underlying cause of many neurological and psychiatric disorders. Synaptic …

The major types of glial cells—astrocytes, microglia, and cells of the oligodendroglial
lineage—are known to express functional metabotropic and ionotropic GABA receptors …

The amino acid γ-aminobutiric acid (GABA) is a major inhibitory transmitter in the vertebrate
central nervous system (CNS) where it can be released by neurons and by glial cells …

Since it was first generally accepted that the two amino acids glutamate and GABA act as
principal neurotransmitters, several landmark discoveries relating to this function have been …