Childhood trauma as a cause of psychosis: linking genes, psychology, and biology

R Van Winkel, M Van Nierop… - The Canadian …, 2013 - journals.sagepub.com
Recent studies have provided robust evidence for an association between childhood trauma
(CT) and psychosis. Meta-analyses have quantified the association, pointing to odds ratios …

Evidence that the association of childhood trauma with psychosis and related psychopathology is not explained by gene-environment correlation: A monozygotic twin …

A Lecei, J Decoster, M De Hert, C Derom… - Schizophrenia …, 2019 - Elsevier
Background Converging evidence supports childhood trauma as possible causal risk for
psychosis and related psychopathology. However, studies have shown that baseline …

Childhood trauma and psychosis: a case-control and case-sibling comparison across different levels of genetic liability, psychopathology, and type of trauma

M Heins, C Simons, T Lataster… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: The associations of two types of childhood trauma (abuse and neglect) with
psychosis symptom domains were investigated in subjects with psychotic illness, high …

Childhood trauma and psychotic disorders: a systematic, critical review of the evidence

S Bendall, HJ Jackson, CA Hulbert… - Schizophrenia …, 2008 - academic.oup.com
There is controversy over whether childhood trauma (CT) is a causal factor in the
development of psychosis. This review aims to identify and critically analyze the association …

Does childhood trauma play a role in the aetiology of psychosis? A review of recent evidence

H Coughlan, M Cannon - BJPsych Advances, 2017 - cambridge.org
There has been a resurgence of interest in the role of childhood trauma in the aetiology of
psychosis. In this review, recent findings on the association between childhood trauma and …

Childhood trauma and psychosis-what is the evidence?

I Schäfer, HL Fisher - Dialogues in clinical neuroscience, 2011 - Taylor & Francis
In the last decade, a substantial number of population-based studies have suggested that
childhood trauma is a risk factor for psychosis. In several studies, the effects held after …

[PDF][PDF] The preeminent role of childhood abuse and neglect in vulnerability to major psychiatric disorders: toward elucidating the underlying neurobiological …

CB Nemeroff, E Binder - Journal of the American Academy of Child & …, 2014 - academia.edu
More than 3 decades ago, our group and others1, 2 suggested, based on results from
laboratory animal studies, that trauma early in life in the form of child abuse and/or neglect …

Childhood trauma and children's emerging psychotic symptoms: a genetically sensitive longitudinal cohort study

L Arseneault, M Cannon, HL Fisher… - American journal of …, 2011 - Am Psychiatric Assoc
Objective: Using longitudinal and prospective measures of trauma during childhood, the
authors assessed the risk of developing psychotic symptoms associated with maltreatment …

Toward a unified theory of childhood trauma and psychosis: a comprehensive review of epidemiological, clinical, neuropsychological and biological findings

B Misiak, M Krefft, T Bielawski, AA Moustafa… - Neuroscience & …, 2017 - Elsevier
There is a growing body of research focused on the relationship between childhood trauma
and the risk of developing psychosis. Numerous studies, including many large-scale …

Childhood trauma may increase risk of psychosis and mood disorder in genetically high-risk children and adolescents by enhancing the accumulation of risk …

N Berthelot, J Garon-Bissonnette… - Schizophrenia …, 2022 - academic.oup.com
Background Genetically high-risk children carry indicators of brain dysfunctions that adult
patients with schizophrenia or bipolar disorder display. The accumulation of risk indicators …