CALCIUM-DEPENDENT potassium (Kca) channels carry ionic currents that regulate
important cellular functions1–3. Like some other ion channels4–10, Kca channels are …

K+ channels represent the most complex class of voltage‐gated ion channels from both
functional and structural standpoints. In the heart these channels are responsible for the …

Background and purpose: Positive modulators of small conductance Ca2+‐activated K+
channels (SK1, SK2, and SK3) exert hyperpolarizing effects that influence the activity of …

We describe here (1) the heterogeneous expression of Ca2+‐independent transient (A‐
type) K+ channel α‐subunits (Kv1. 4, Kv3. 3, Kv3. 4, Kv4. 2 and Kv4. 3) in rat smooth muscle …

Abstract Large-conductance Ca 2+-activated K+(BK Ca) channels are sensitive to both
voltage and internal [Ca 2+] and are found in many tissues. Their physiological roles range …

Outward rectifier K+ channels have a characteristic structure with six transmembrane
segments and one pore region. A new member of this family of transmembrane proteins has …

Calcium-activated potassium channels mediate many biologically important functions in
electrically excitable cells. Despite recent progress in the molecular analysis of voltage …

The purpose of the present study was to examine how apamin interacts with the three
cloned subtypes of small-conductance Ca 2+-activated K+ channels (hSK1, rSK2 and rSK3) …

Mammalian high conductance, calcium-activated potassium (maxi-K) channels are
composed of two dissimilar subunits, a and p. We have examined the functional contribution …

Voltage-dependent potassium, sodium and calcium ion channels may share a common
mechanism of activation, in which the conserved S4 sequence acts as the primary voltage …