W Xu, T Chen, Y Pei, H Guo, Z Li, Y Yang… - Frontiers in …, 2021 - frontiersin.org
Characterization of the bacterial composition and functional repertoires of microbiome samples is the most common application of metagenomics. Although deep whole …
The human microbiome has emerged as a major player in regulating human health and disease. Translational studies of the microbiome have the potential to indicate clinical …
AJ La Reau, NB Strom, E Filvaroff, K Mavrommatis… - Scientific reports, 2023 - nature.com
The microbiome is known to play a role in many human diseases, but identifying key microbes and their functions generally requires large studies due to the vast number of …
J Mas-Lloret, M Obón-Santacana, G Ibáñez-Sanz… - Scientific data, 2020 - nature.com
The gut microbiome has a fundamental role in human health and disease. However, studying the complex structure and function of the gut microbiome using next generation …
J Jovel, J Patterson, W Wang, N Hotte… - Frontiers in …, 2016 - frontiersin.org
The advent of next generation sequencing (NGS) has enabled investigations of the gut microbiome with unprecedented resolution and throughput. This has stimulated the …
DM O'Sullivan, RM Doyle, S Temisak, N Redshaw… - Scientific Reports, 2021 - nature.com
Despite the advent of whole genome metagenomics, targeted approaches (such as 16S rRNA gene amplicon sequencing) continue to be valuable for determining the microbial …
F Yang, J Sun, H Luo, H Ren, H Zhou, Y Lin… - …, 2020 - academic.oup.com
Background Shotgun metagenomic sequencing has improved our understanding of the human gut microbiota. Various DNA extraction methods have been compared to find …
Although microbial communities are associated with human, environmental, plant, and animal health, there exists no cost-effective method for precisely characterizing species and …
Both the host microbiome and the microbiome of the built environment can have profound impacts on human health. While prior studies have suggested that the variability introduced …