Dendritic cells (DC) are powerful antigen presenting cells, which have the unique capacity to
stimulate naive T cells. In spite of the well-known decline of T cell function in old age, little …

Dendritic cells (DC) are professional antigen presenting cells which are essential for the
initiation of an immune response. Recently we demonstrated that DC, which had been …

Dendritic cells (DC) are known as the most efficient antigen-presenting cell type to activate T
cells and are key modulators of the immune response. Due to their central role in …

Dendritic cells are antigen‐presenting cells (APC), which are crucial for the initiation of an
immune response. In spite of the well known decline of immune function in old age, no …

Dendritic cells (DCs) are the single most central player in all immune responses. To assess
whether DC alterations may contribute to the immune dysregulation that affects the elderly …

CD4+ T cells regulate humoral and cell-mediated immune responses, which are
progressively impaired in aging, resulting in susceptibility to infections and cancer. Dendritic …

Dendritic cells (DCs) play a critical role in linking innate and adaptive immunity. A role of
DCs in immunosenescence and chronic inflammation associated with aging has not been …

Aging leads to reduced immunity, especially adaptive responses. A key deficiency is the
poor ability to mount robust antibody response. Although intrinsic alterations in B cells with …

Aging is associated with a progressive decline in T cell function, chronic inflammation,
hyperimmunoglobulinemia, autoimmunity, poor response to vaccines, and increased …

Aging represents a state of paradox where chronic inflammation is associated with declining
immune responses. Dendritic cells (DCs) are the major APCs responsible for initiating an …