[HTML][HTML] Bioinformatics insights into the genes and pathways on severe COVID-19 pathology in patients with comorbidities

A Mujalli, KS Alghamdi, KK Nasser, N Al-Rayes… - Frontiers in …, 2022 - frontiersin.org
Background: Coronavirus disease (COVID-19) infection is known for its severe clinical
pathogenesis among individuals with pre-existing comorbidities. However, the molecular …

Integrated Transcriptomics and Network Analysis of Potential Mechanisms and Health Effects of Convalescent COVID-19 Patients

S Chujan, W Nakareangrit, T Suriyo… - … and Biology Insights, 2023 - journals.sagepub.com
Coronaviral disease 2019 (COVID-19) is a recent pandemic disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there are still cases of …

Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions

Z Nain, SK Barman, MM Sheam, SB Syed… - Briefings in …, 2021 - academic.oup.com
Despite the association of prevalent health conditions with coronavirus disease 2019
(COVID-19) severity, the disease-modifying biomolecules and their pathogenetic …

Identification of Comorbidities, Genomic Associations, and Molecular Mechanisms for COVID‐19 Using Bioinformatics Approaches

SBS Omit, S Akhter, HK Rana… - BioMed Research …, 2023 - Wiley Online Library
Several studies have been done to identify comorbidities of COVID‐19. In this work, we
developed an analytical bioinformatics framework to reveal COVID‐19 comorbidities, their …

Identifying molecular insight of synergistic complexities for SARS-CoV-2 infection with pre-existing type 2 diabetes

MB Islam, UN Chowdhury, Z Nain, S Uddin… - Computers in biology …, 2021 - Elsevier
The ongoing COVID-19 outbreak, caused by SARS-CoV-2, has posed a massive threat to
global public health, especially to people with underlying health conditions. Type 2 diabetes …

Integrated Bioinformatics Exploration and Preliminary Clinical Verification for the Identification of Crucial Biomarkers in Severe Cases of COVID-19

Z Huang, Z Cheng, X Deng, Y Yang, N Sun… - Journal of …, 2024 - Taylor & Francis
Background Coronavirus disease 2019 (COVID-19) is a respiratory infectious illness caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The objective of this …

[HTML][HTML] Bioinformatics and system biology approach to identify the influences among COVID-19, ARDS and sepsis

P Li, T Li, Z Zhang, X Dai, B Zeng, Z Li, Z Li - Frontiers in Immunology, 2023 - frontiersin.org
Background Severe coronavirus disease 2019 (COVID-19) has led to severe pneumonia or
acute respiratory distress syndrome (ARDS) worldwide. we have noted that many critically ill …

[HTML][HTML] Identification of differentially expressed genes and enriched pathways in SARS-CoV-2/COVID-19 using bioinformatics analysis

AM Alshabi, IA Shaikh, BM Vastrad, CM Vastrad - 2020 - europepmc.org
Background: The exact molecular mechanisms of the progression of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remain unclear. The current …

Bioinformatics and system biology approach to identify the influences of COVID-19 on cardiovascular and hypertensive comorbidities

A Nashiry, S Sarmin Sumi, S Islam… - Briefings in …, 2021 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals that
have hypertension or cardiovascular comorbidities have an elevated risk of serious …

[HTML][HTML] Molecular signatures in the progression of COVID-19 severity

R De, RK Azad - Scientific Reports, 2022 - nature.com
SARS-CoV-2 is the causative agent of COVID-19 that has infected over 642 million and
killed over 6.6 million people around the globe. Underlying a wide range of clinical …