The genetics of inflammatory bowel disease

J Van Limbergen, RK Russell, ER Nimmo… - Official journal of the …, 2007 - journals.lww.com
Great progress in the understanding of the molecular genetics of inflammatory bowel
disease (IBD) has been made over the last 10 years. Strong epidemiological evidence …

Inflammatory bowel disease in the Asia–Pacific area: a comparison with developed countries and regional differences

V Ahuja, RK Tandon - Journal of digestive diseases, 2010 - Wiley Online Library
The Asia–Pacific region has been marked as an area with a low incidence of inflammatory
bowel disease (IBD), although confusion always existed as to whether this low incidence …

Recent advances in the genetics of inflammatory bowel disease

B Newman, KA Siminovitch - Current opinion in gastroenterology, 2005 - journals.lww.com
The application of genetic information to diagnosis and risk prediction in inflammatory bowel
disease will require comprehensive knowledge of the relevant susceptibility alleles …

The genetic background of inflammatory bowel disease: from correlation to causality

WTC Uniken Venema, MD Voskuil… - The Journal of …, 2017 - Wiley Online Library
Recent studies have greatly improved our insight into the genetic background of
inflammatory bowel disease (IBD). New high‐throughput technologies and large‐scale …

[HTML][HTML] Clinical characteristics and treatment of inflammatory bowel disease: a comparison of Eastern and Western perspectives

SJ Park, WH Kim, JH Cheon - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic, relapsing intestinal inflammatory disorder
with unidentified causes. Both environmental factors and genetic aspects are believed to be …

Clinical implications of inflammatory bowel disease genetics on phenotype

FJR Cummings, DP Jewell - Inflammatory bowel diseases, 2005 - academic.oup.com
The genetic revolution has been with us for over a decade now. We have yet to see this
impacting the care of patients except in a few rare examples. However, progress has been …

The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction

M Pierik, H Yang, MM Barmada… - Inflammatory bowel …, 2005 - academic.oup.com
Abstract Background and Aims The inflammatory bowel diseases (IBDs) Crohn's disease
(CD) and ulcerative colitis are complex disorders with an important genetic determinant. One …

Update on the genetics of inflammatory bowel disease

RH Duerr - Journal of clinical gastroenterology, 2003 - journals.lww.com
There is a general consensus that interplay of genetic and environmental factors leads to an
overactive mucosal immune response, which mediates the tissue damage in inflammatory …

[HTML][HTML] Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across …

SK Yang, M Hong, W Zhao, Y Jung, J Baek, N Tayebi… - Gut, 2014 - gut.bmj.com
Objective Crohn9s disease (CD) is an intractable inflammatory bowel disease (IBD) of
unknown cause. Recent meta-analysis of the genome-wide association studies (GWAS) and …

Impact of genes and the environment on the pathogenesis and disease course of inflammatory bowel disease

M Zhao, J Burisch - Digestive diseases and sciences, 2019 - Springer
Crohn's disease and ulcerative colitis constitute two major subgroups of inflammatory bowel
diseases (IBD), a group of complex polygenic diseases characterized by chronic and …