V Ahuja, RK Tandon - Journal of digestive diseases, 2010 - Wiley Online Library
The Asia–Pacific region has been marked as an area with a low incidence of inflammatory bowel disease (IBD), although confusion always existed as to whether this low incidence …
B Newman, KA Siminovitch - Current opinion in gastroenterology, 2005 - journals.lww.com
The application of genetic information to diagnosis and risk prediction in inflammatory bowel disease will require comprehensive knowledge of the relevant susceptibility alleles …
WTC Uniken Venema, MD Voskuil… - The Journal of …, 2017 - Wiley Online Library
Recent studies have greatly improved our insight into the genetic background of inflammatory bowel disease (IBD). New high‐throughput technologies and large‐scale …
SJ Park, WH Kim, JH Cheon - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic, relapsing intestinal inflammatory disorder with unidentified causes. Both environmental factors and genetic aspects are believed to be …
The genetic revolution has been with us for over a decade now. We have yet to see this impacting the care of patients except in a few rare examples. However, progress has been …
M Pierik, H Yang, MM Barmada… - Inflammatory bowel …, 2005 - academic.oup.com
Abstract Background and Aims The inflammatory bowel diseases (IBDs) Crohn's disease (CD) and ulcerative colitis are complex disorders with an important genetic determinant. One …
RH Duerr - Journal of clinical gastroenterology, 2003 - journals.lww.com
There is a general consensus that interplay of genetic and environmental factors leads to an overactive mucosal immune response, which mediates the tissue damage in inflammatory …
SK Yang, M Hong, W Zhao, Y Jung, J Baek, N Tayebi… - Gut, 2014 - gut.bmj.com
Objective Crohn9s disease (CD) is an intractable inflammatory bowel disease (IBD) of unknown cause. Recent meta-analysis of the genome-wide association studies (GWAS) and …
M Zhao, J Burisch - Digestive diseases and sciences, 2019 - Springer
Crohn's disease and ulcerative colitis constitute two major subgroups of inflammatory bowel diseases (IBD), a group of complex polygenic diseases characterized by chronic and …