Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans

C Huang, T Haritunians, DT Okou, DJ Cutler, ME Zwick… - Gastroenterology, 2015 - Elsevier
Background & Aims Inflammatory bowel disease (IBD) has familial aggregation in African
Americans (AAs), but little is known about the molecular genetic susceptibility. Mapping …

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

RK Weersma, PCF Stokkers, I Cleynen… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Inflammatory bowel diseases (IBD)—Crohn's disease (CD) and ulcerative
colitis (UC)—are chronic gastrointestinal inflammatory disorders with a complex genetic …

Clinical relevance of advances in genetics and pharmacogenetics of IBD

T Ahmad, CP Tamboli, D Jewell, JF Colombel - Gastroenterology, 2004 - Elsevier
Crohn's disease and ulcerative colitis result from an inappropriate response of the mucosal
immune system to the normal enteric flora in a genetically susceptible individual. During the …

Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease

HH Uhlig - Gut, 2013 - gut.bmj.com
Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, has
multifactorial aetiology with complex interactions between genetic and environmental …

Inflammatory bowel disease: progress towards a gene

DA van Heel, J Satsangi, AH Carey… - Canadian Journal of …, 2000 - hindawi.com
The pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD) is still unknown, but
the importance of genetic susceptibility has been clearly shown by epidemiological data …

Familial risk of inflammatory bowel disease: a population-based cohort study 1977–2011

FT Moller, V Andersen, J Wohlfahrt… - Official journal of the …, 2015 - journals.lww.com
OBJECTIVES: Estimates of familial risk of inflammatory bowel diseases (IBDs), Crohn's
disease (CD), and ulcerative colitis (UC) are needed for counseling of patients and could be …

Pediatric inflammatory bowel disease: clinical and molecular genetics

V Biank, U Broeckel… - Inflammatory bowel …, 2007 - academic.oup.com
Pediatric-onset inflammatory bowel disease (IBD) is characterized by distinct phenotypic
differences compared to adult-onset IBD. This raises the question whether early (pediatric) …

[HTML][HTML] Review of inflammatory bowel disease in China

L Ye, Q Cao, J Cheng - The Scientific World Journal, 2013 - hindawi.com
Inflammatory bowel disease mainly consisting of ulcerative colitis and Crohn's disease has
been rising gradually during the last two decades in China. In this review article, we provide …

Genome-wide association study identifies African-specific susceptibility loci in African Americans with inflammatory bowel disease

SR Brant, DT Okou, CL Simpson, DJ Cutler… - Gastroenterology, 2017 - Elsevier
Background & Aims The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and
Crohn's disease (CD) cause significant morbidity and are increasing in prevalence among …

Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study

SC Ng, W Tang, JY Ching, M Wong, CM Chow, AJ Hui… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Inflammatory bowel diseases (IBD) are becoming more common in
Asia, but epidemiologic data are lacking. The Asia-Pacific Crohn's and Colitis Epidemiology …