Inflammatory bowel disease (IBD) is a multifactorial disorder, with both genetic and
environmental factors contributing to the two clinical phenotypes of Crohn's disease (CD) …

Background Inflammatory bowel disease is uncommon in Southeast Asia but is increasing in
incidence. The epidemiology and phenotype of Crohn disease (CD) in the Chinese …

Background Genetic predisposition to inflammatory bowel disease (IBD) has been shown by
epidemiological and linkage studies. Genetic linkage of IBD to chromosome 16 has been …

Background Although the prevalence of inflammatory bowel disease (IBD) is reported to
have reached a plateau in Western countries, it is increasing in Asia. The etiology of IBD is …

Inflammatory bowel disease (IBD) includes two clinical subtypes: Crohn disease (CD) and
ulcerative colitis (UC). The general prevalence is about 1.0%-2.0% in Western countries. It is …

Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …

OBJECTIVES: Three variants of the CARD15/NOD2 gene (SNP8, SNP12, and SNP13) have
been associated with Crohn's disease (CD). We assessed the impact of NOD2 variants on …

BACKGROUND/OBJECTIVE: Variants in the interleukin-23 receptor (IL23R) and the
autophagy-related 16-like 1 (ATG16L1) genes have been associated with an increased risk …

Background Recent genome-wide association studies in Caucasian populations identified
IL23R and ATG16L1 as susceptibility genes to Crohn's disease (CD). We tested 5 IL23R …

Background The aims were to analyze two novel NOD2 variants (rs2066843 and
rs2076756) in a large cohort of patients with inflammatory bowel disease and to elucidate …