Basic concepts of activity-based interventions for improved recovery of motor function after spinal cord injury

RR Roy, SJ Harkema, VR Edgerton - Archives of physical medicine and …, 2012 - Elsevier
Roy RR, Harkema SJ, Edgerton VR. Basic concepts of activity-based interventions for
improved recovery of motor function after spinal cord injury. Spinal cord injury (SCI) is a …

Epidural electrical stimulation: a review of plasticity mechanisms that are hypothesized to underlie enhanced recovery from spinal cord injury with stimulation

JT Eisdorfer, RD Smit, KM Keefe, MA Lemay… - Frontiers in Molecular …, 2020 - frontiersin.org
Spinal cord injury (SCI) often results in life-long sensorimotor impairment. Spontaneous
recovery from SCI is limited, as supraspinal fibers cannot spontaneously regenerate to form …

Recovery of control of posture and locomotion after a spinal cord injury: solutions staring us in the face

AJ Fong, RR Roy, RM Ichiyama, I Lavrov… - Progress in brain …, 2009 - Elsevier
Over the past 20 years, tremendous advances have been made in the field of spinal cord
injury research. Yet, consumed with individual pieces of the puzzle, we have failed as a …

Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans

CA Angeli, VR Edgerton, YP Gerasimenko… - Brain, 2014 - academic.oup.com
Previously, we reported that one individual who had a motor complete, but sensory
incomplete spinal cord injury regained voluntary movement after 7 months of epidural …

Noninvasive reactivation of motor descending control after paralysis

YP Gerasimenko, DC Lu, M Modaber… - Journal of …, 2015 - liebertpub.com
The present prognosis for the recovery of voluntary control of movement in patients
diagnosed as motor complete is generally poor. Herein we introduce a novel and …

[HTML][HTML] Plasticity after spinal cord injury: relevance to recovery and approaches to facilitate it

SM Onifer, GM Smith, K Fouad - Neurotherapeutics, 2011 - Elsevier
Motor, sensory, and autonomic functions can spontaneously return or recover to varying
extents in both humans and animals, regardless of the traumatic spinal cord injury (SCI) …

Reorganization and preservation of motor control of the brain in spinal cord injury: a systematic review

KJ Kokotilo, JJ Eng, A Curt - Journal of neurotrauma, 2009 - liebertpub.com
Reorganization of brain function in people with CNS damage has been identified as one of
the fundamental mechanisms involved in the recovery of sensorimotor function. Spinal cord …

Plasticity of corticospinal neural control after locomotor training in human spinal cord injury

M Knikou - Neural plasticity, 2012 - Wiley Online Library
Spinal lesions substantially impair ambulation, occur generally in young and otherwise
healthy individuals, and result in devastating effects on quality of life. Restoration of …

Therapeutic stimulation for restoration of function after spinal cord injury

A Ievins, CT Moritz - Physiology, 2017 - journals.physiology.org
Paralysis due to spinal cord injury can severely limit motor function and independence. This
review summarizes different approaches to electrical stimulation of the spinal cord designed …

From cortex to cord: motor circuit plasticity after spinal cord injury

AR Brown, M Martinez - Neural regeneration research, 2019 - journals.lww.com
Spinal cord injury is associated with chronic sensorimotor deficits due to the interruption of
ascending and descending tracts between the brain and spinal cord. Functional recovery …