Resveratrol has been reported to protect against cerebral ischemia/reperfusion (I/R) injury in
rats, but the underlying mechanism is unclear. In the current study, we examined whether …

The inflammatory response in the cerebral cortex serves an important role in the progression
of secondary injury following traumatic brain injury (TBI). The NLR family pyrin domain …

Previous studies have demonstrated resveratrol (RSV) has beneficial effects in early brain
injury (EBI) after subarachnoid hemorrhage (SAH). However, the beneficial effects of RSV …

Background Our previous studies demonstrated that autophagy alleviates cerebral I/R injury
by inhibiting NLRP3 inflammasome-mediated inflammation. 6-Gingerol, a phenolic …

Previous research has demonstrated that traumatic brain injury (TBI) activates autophagy
and a neuroinflammatory cascade that contributes to substantial neuronal damage and …

Sepsis‐associated encephalopathy (SAE) is characterized as brain dysfunction associated
with sepsis. In this study we sought to investigate the effects of resveratrol in mice with SAE …

Resveratrol is a natural polyphenolic compound with a wide range of biological activities
such as antioxidant, anti-carcinogenic, anti-obesity, anti-aging, anti-inflammatory …

Background The NOD-like receptor family pyrin domain-containing 3 (NLRP3)
inflammasome is an important mediator of neuroinflammatory responses that regulates …

NLRP3 inflammasome is a key mediator in ischemic stroke-induced neuroinflammation and
subsequent brain injury. Our previous study demonstrated the potent activity of Pien-Tze …

The nod-like receptor protein 3 (NLRP3) inflammasome has a critical role in cerebral
ischemic injury, and autophagy is related to activation of the inflammasome under oxidative …