Increasing evidence has revealed the importance of cancer stem cells (CSCs) in
carcinogenesis. Although liver CSCs have been identified in hepatocellular carcinoma …

This study characterized cancer stem cells (CSCs) in hepatocellular carcinoma (HCC) cell
lines, tumor specimens, and blood samples. The CD90+ cells, but not the CD90− cells, from …

Background & Aims: Recent efforts in stem cell biology suggest that tumors are organized in
a hierarchy of heterogeneous cell populations and that the capability to maintain tumor …

Both our previous study and other reports have suggested that CD133, originally classified
as a hematopoietic stem cell marker, could be used for enrichment of cancer stem cells …

The cancer stem cell (CSC) hypothesis was first proposed over 40 years ago. Advances in
CSC isolation were first achieved in hematological malignancies, with the first CSC …

Recent findings suggest that the presence of cancer stem cells could be linked with patients'
survival. We profiled suggested cancer stem cell markers in tissue specimens of …

Solid tumors are thought to contain cancer stem cells (CSCs) as a distinct population
responsible for tumor relapse and metastasis due to their abilities to self-renew, differentiate …

Abstract Background & Aims. Major burdens in the treatment of hepatocellular
carcinoma (HCC) are the high percentage of recurrence and resistance to chemotherapy …

BACKGROUND: Cancer stem cells (CSCs) are thought to be a critical subpopulation in
tumor development, progression, metastasis and recurrence, and the identification of these …

Although the “cancer stem cell (CSC)” hypothesis was first proposed roughly 50years ago,
recent progress in stem cell biology and technologies has successfully achieved the …