Identification of immunodominant epitopes on the membrane protein of the severe acute respiratory syndrome-associated coronavirus

Y He, Y Zhou, P Siddiqui, J Niu… - Journal of clinical …, 2005 - Am Soc Microbiol
Similar to other coronaviruses, the membrane (M) protein of severe acute respiratory
syndrome-associated coronavirus (SARS-CoV) is a major transmembrane glycoprotein with …

Receptor-binding domain of severe acute respiratory syndrome coronavirus spike protein contains multiple conformation-dependent epitopes that induce highly …

Y He, H Lu, P Siddiqui, Y Zhou… - The Journal of Immunology, 2005 - journals.aai.org
The spike (S) protein of severe acute respiratory syndrome associated coronavirus (SARS-
CoV) is a major antigenic determinant capable of inducing protective immunity. Recently, a …

Longitudinal profile of antibodies against SARS‐coronavirus in SARS patients and their clinical significance

H Mo, G Zeng, X Ren, H Li, C Ke, Y Tan, C Cai… - …, 2006 - Wiley Online Library
Background: Severe acute respiratory syndrome (SARS) is a newly discovered disease
caused by a novel coronavirus. The present study studied the longitudinal profile of …

Immunodominant SARS coronavirus epitopes in humans elicited both enhancing and neutralizing effects on infection in non-human primates

Q Wang, L Zhang, K Kuwahara, L Li, Z Liu… - ACS infectious …, 2016 - ACS Publications
Severe acute respiratory syndrome (SARS) is caused by a coronavirus (SARS-CoV) and
has the potential to threaten global public health and socioeconomic stability. Evidence of …

Long-term persistence of robust antibody and cytotoxic T cell responses in recovered patients infected with SARS coronavirus

T Li, J Xie, Y He, H Fan, L Baril, Z Qiu, Y Han, W Xu… - PloS one, 2006 - journals.plos.org
Most of the individuals infected with SARS coronavirus (SARS-CoV) spontaneously
recovered without clinical intervention. However, the immunological correlates associated …

Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate

WH Chen, L Du, SM Chag, C Ma… - Human vaccines & …, 2014 - Taylor & Francis
Development of vaccines for preventing a future pandemic of severe acute respiratory
syndrome (SARS) caused by SARS coronavirus (SARS-CoV) and for biodefense …

Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine

Y He, Y Zhou, S Liu, Z Kou, W Li, M Farzan… - … and biophysical research …, 2004 - Elsevier
The spike (S) protein of severe acute respiratory syndrome (SARS) coronavirus (CoV), a
type I transmembrane envelope glycoprotein, consists of S1 and S2 domains responsible for …

T cell responses to whole SARS coronavirus in humans

CK Li, H Wu, H Yan, S Ma, L Wang… - The Journal of …, 2008 - journals.aai.org
Effective vaccines should confer long-term protection against future outbreaks of severe
acute respiratory syndrome (SARS) caused by a novel zoonotic coronavirus (SARS-CoV) …

Seroprevalence of IgG antibodies to SARS-coronavirus in asymptomatic or subclinical population groups

GM Leung, WW Lim, LM Ho, TH Lam… - Epidemiology & …, 2006 - cambridge.org
We systematically reviewed the current understanding of human population immunity
against SARS-CoV in different groups, settings and geography. Our meta-analysis, which …

Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcγRII-dependent entry into B cells in vitro

YW Kam, F Kien, A Roberts, YC Cheung… - Vaccine, 2007 - Elsevier
Vaccine-induced antibodies can prevent or, in the case of feline infectious peritonitis virus,
aggravate infections by coronaviruses. We investigated whether a recombinant native full …