Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces …
We developed a severe acute respiratory syndrome (SARS) subunit recombinant protein
vaccine candidate based on a high-yielding, yeast-engineered, receptor-binding domain …
vaccine candidate based on a high-yielding, yeast-engineered, receptor-binding domain …
An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif
The rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
such as the Omicron variants that are highly transmissible and immune evasive …
such as the Omicron variants that are highly transmissible and immune evasive …
Antigenic and immunogenic characterization of recombinant baculovirus-expressed severe acute respiratory syndrome coronavirus spike protein: implication for …
Y He, J Li, S Heck, S Lustigman, S Jiang - Journal of virology, 2006 - Am Soc Microbiol
The spike (S) glycoprotein of severe acute respiratory syndrome coronavirus (SARS-CoV)
mediates the receptor interaction and immune recognition and is considered a major target …
mediates the receptor interaction and immune recognition and is considered a major target …
A recombinant baculovirus-expressed S glycoprotein vaccine elicits high titers of SARS-associated coronavirus (SARS-CoV) neutralizing antibodies in mice
Z Zhou, P Post, R Chubet, K Holtz, C McPherson… - Vaccine, 2006 - Elsevier
A recombinant SARS-CoV spike (S) glycoprotein vaccine produced in insect cells in a pre-
clinical development stage is described. A truncated version of S glycoprotein, containing …
clinical development stage is described. A truncated version of S glycoprotein, containing …
Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness
J Sui, M Deming, B Rockx, RC Liddington… - Journal of …, 2014 - Am Soc Microbiol
The receptor binding domain (RBD) of the spike (S) glycoprotein of severe acute respiratory
syndrome coronavirus (SARS-CoV) is a major target of protective immunity in vivo. Although …
syndrome coronavirus (SARS-CoV) is a major target of protective immunity in vivo. Although …
Amino acids 270 to 510 of the severe acute respiratory syndrome coronavirus spike protein are required for interaction with receptor
GJ Babcock, DJ Esshaki, WD Thomas Jr… - Journal of …, 2004 - Am Soc Microbiol
ABSTRACT A novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-
CoV), has recently been identified as the causative agent of severe acute respiratory …
CoV), has recently been identified as the causative agent of severe acute respiratory …
[HTML][HTML] Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein
Y Zhi, GP Kobinger, H Jordan, K Suchma, SR Weiss… - Virology, 2005 - Elsevier
The causative agent of severe acute respiratory syndrome (SARS) has been identified as a
new type of coronavirus, SARS-associated coronavirus (SARS-CoV). CD8 T cells play an …
new type of coronavirus, SARS-associated coronavirus (SARS-CoV). CD8 T cells play an …
S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected …
H Hofmann, K Hattermann, A Marzi… - Journal of …, 2004 - Am Soc Microbiol
The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) causes severe
pneumonia with a fatal outcome in approximately 10% of patients. SARS-CoV is not closely …
pneumonia with a fatal outcome in approximately 10% of patients. SARS-CoV is not closely …
[HTML][HTML] A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo
CW Day, R Baric, SX Cai, M Frieman, Y Kumaki… - Virology, 2009 - Elsevier
Severe acute respiratory syndrome (SARS) is a highly lethal emerging disease caused by
coronavirus SARS-CoV. New lethal animal models for SARS were needed to facilitate …
coronavirus SARS-CoV. New lethal animal models for SARS were needed to facilitate …
Antibody-dependent enhancement of SARS coronavirus infection and its role in the pathogenesis of SARS
MS Yip, HL Leung, PH Li, CY Cheung, I Dutry… - Hong Kong Medical …, 2016 - hub.hku.hk
1. Anti-SARS-CoV spike antibodies promote infection of primary human immune cells by
SARS-CoV. 2. The antibody-dependent enhancement (ADE) infection pathway grants SARS …
SARS-CoV. 2. The antibody-dependent enhancement (ADE) infection pathway grants SARS …