Identification of immunodominant sites on the spike protein of severe acute respiratory syndrome (SARS) coronavirus: implication for developing SARS diagnostics …
Y He, Y Zhou, H Wu, B Luo, J Chen, W Li… - The Journal of …, 2004 - journals.aai.org
The spike (S) protein of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV)
is not only responsible for receptor binding and virus fusion, but also a major Ag among the …
is not only responsible for receptor binding and virus fusion, but also a major Ag among the …
T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice
J Zhao, J Zhao, S Perlman - Journal of virology, 2010 - Am Soc Microbiol
ABSTRACT A dysregulated innate immune response and exuberant cytokine/chemokine
expression are believed to be critical factors in the pathogenesis of severe acute respiratory …
expression are believed to be critical factors in the pathogenesis of severe acute respiratory …
Lack of cross-neutralization by SARS patient sera towards SARS-CoV-2
DE Anderson, CW Tan, WN Chia… - Emerging microbes & …, 2020 - Taylor & Francis
Despite initial findings indicating that SARS-CoV and SARS-CoV-2 are genetically related
belonging to the same virus species and that the two viruses used the same entry receptor …
belonging to the same virus species and that the two viruses used the same entry receptor …
Immunogenicity and protective efficacy in monkeys of purified inactivated Vero-cell SARS vaccine
E Qin, H Shi, L Tang, C Wang, G Chang, Z Ding… - Vaccine, 2006 - Elsevier
BACKGROUND: In 2003, severe acute respiratory syndrome (SARS) resulted in hundreds of
infections and deaths globally. We aim to assess immunogenicity and protective efficacy of …
infections and deaths globally. We aim to assess immunogenicity and protective efficacy of …
Assessment of immunoreactive synthetic peptides from the structural proteins of severe acute respiratory syndrome coronavirus
J Wang, J Wen, J Li, J Yin, Q Zhu, H Wang… - Clinical …, 2003 - academic.oup.com
Background: The widespread threat of severe acute respiratory syndrome (SARS) to human
life has spawned challenges to develop fast and accurate analytical methods for its early …
life has spawned challenges to develop fast and accurate analytical methods for its early …
Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: implications for a subunit vaccine
AN Zakhartchouk, C Sharon, M Satkunarajah… - Vaccine, 2007 - Elsevier
We studied the immunogenicity of an anti-SARS subunit vaccine comprised of the fragment
of the SARS coronavirus (SARS-CoV) spike protein amino acids 318–510 (S318–510) …
of the SARS coronavirus (SARS-CoV) spike protein amino acids 318–510 (S318–510) …
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
The emergence of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants of concern (VOCs) and potential future spillovers of SARS-like coronaviruses into …
variants of concern (VOCs) and potential future spillovers of SARS-like coronaviruses into …
[HTML][HTML] Neutralizing antibody and protective immunity to SARS coronavirus infection of mice induced by a soluble recombinant polypeptide containing an N-terminal …
H Bisht, A Roberts, L Vogel, K Subbarao, B Moss - Virology, 2005 - Elsevier
A secreted, glycosylated polypeptide containing amino acids 14 to 762 of the SARS
coronavirus (SARS-CoV) spike protein and a polyhistidine tag was expressed in …
coronavirus (SARS-CoV) spike protein and a polyhistidine tag was expressed in …
Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice
K Subbarao, J McAuliffe, L Vogel, G Fahle… - Journal of …, 2004 - Am Soc Microbiol
Following intranasal administration, the severe acute respiratory syndrome (SARS)
coronavirus replicated to high titers in the respiratory tracts of BALB/c mice. Peak replication …
coronavirus replicated to high titers in the respiratory tracts of BALB/c mice. Peak replication …
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice
Z Yang, W Kong, Y Huang, A Roberts, BR Murphy… - Nature, 2004 - nature.com
Public health measures have successfully identified and contained outbreaks of the severe
acute respiratory syndrome (SARS) coronavirus (SARS-CoV),,,,, but concerns remain over …
acute respiratory syndrome (SARS) coronavirus (SARS-CoV),,,,, but concerns remain over …