Background Hydroxychloroquine and chloroquine have been proposed as treatments for
coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from …

Importance Data on the efficacy of hydroxychloroquine for the treatment of coronavirus
disease 2019 (COVID-19) are needed. Objective To determine whether hydroxychloroquine …

Despite several studies designed to evaluate the efficacy of chloroquine and
hydroxychloroquine in the treatment of coronavirus disease 2019 (COVID-19), there is still …

The COVID-19 pandemic is showing an exponential growth, mandating an urgent need to
develop an effective treatment. Indeed, to date, a well-established therapy is still lacking. We …

Background Effective therapies to combat coronavirus 2019 (COVID-19) are urgently
needed. Hydroxychloroquine (HCQ) has in vitro antiviral activity against severe acute …

Background Hydroxychloroquine has been widely administered to patients with Covid-19
without robust evidence supporting its use. Methods We examined the association between …

Summary Background Previous Randomised controlled trials (RCT) evaluating chloroquine
and hydroxychloroquine in non-hospitalised COVID-19 patients have found no significant …

Objectives Clinical studies of chloroquine (CQ) and hydroxychloroquine (HCQ) in COVID-19
disease reported conflicting results. We sought to systematically evaluate the effect of CQ …

Background: Identification of therapies to prevent severe COVID-19 remains a priority. We
sought to determine whether hydroxychloroquine treatment for outpatients with SARS-CoV-2 …

Background There is no effective therapy for COVID-19. Hydroxychloroquine (HCQ) and
chloroquine (CQ) have been used for its treatment but their safety and efficacy remain …