Among the pathogenic processes contributing to dopaminergic neuron (DN) death in
Parkinson disease (PD), evidence points to non–cell-autonomous mechanisms, particularly …

Inflammation and oxidative stress have been closely associated with the pathogenesis of
neurodegenerative disorders, including Parkinson's disease (PD). The expression of …

Glucocorticoids (GCs) exert via glucocorticoid receptors (GRs) potent anti‐inflammatory and
immunosuppressive effects. Emerging evidence indicates that an inflammatory process is …

In CNS, glucocorticoids (GCs) activate both GC receptor (GR) and mineralocorticoid
receptor (MR), whereas GR is widely expressed, the expression of MR is restricted …

Inflammation is a characteristic feature of Parkinson's disease (PD). We examined the role of
TLR9 and its regulation by glucocorticoid receptors (GRs) in degeneration of substantia …

Chronic inflammation is a major characteristic feature of Parkinson's disease (PD). Studies
in PD patients show evidence of augmented levels of potent pro-inflammatory molecules eg …

The precise contribution of astrocytes in neuroinflammatory process occurring in Parkinson's
disease (PD) is not well characterized. In this study, using GRCx30CreERT2 mice that are …

PD (Parkinson's disease) is characterized by the selective and progressive loss of DA
neurons (dopaminergic neurons) in the substantia nigra. Inflammation and activation of …

This review is aimed to highlight the importance of stress and glucocorticoids (GCs) in
modulating the inflammatory response of brain microglia and hence its potential involvement …

Both epidemiological and genetic studies support a role of neuroinflammation in the
pathophysiology of Parkinson's disease (PD). Furthermore, post mortem studies confirm the …