Microglia, the resident immune cells of the central nervous system (CNS), monitor the brain
for disturbances of tissue homeostasis by constantly moving their fine processes. Microglia …

Parkinsons' disease (PD), a common neurodegenerative disorder, is characterized by
progressive loss of dopaminergic (DAergic) neurons in the subtantia nigra pars compacta …

Neuroinflammation is recognized as a major factor in Parkinson's disease (PD)
pathogenesis and increasing evidence propose that microglia is the main source of …

Stress, injury, and disease trigger glucocorticoid (GC) elevation. Elevated GCs bind to the
ubiquitously expressed glucocorticoid receptor (GR). While GRs are in every cell in the …

Parkinson's disease (PD) is characterised by degeneration of dopaminergic neurons in the
substantia nigra pars compacta (SNpc). Inflammation may be associated with the …

Neural injury leads to inflammation and activation of microglia that in turn may participate in
progression of neurodegeneration. The mechanisms involved in changing microglial activity …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
degeneration of dopamine neurons in the substantia nigra pars compacta. To date, although …

Dopaminergic cells in the substantia nigra are highly vulnerable to the neurodegenerative
process of Parkinson's disease. Therefore, mechanisms that enhance their susceptibility to …

Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …

Neuroinflammation mediated by microglial activation appears to play an essential role in the
pathogenesis of Parkinson disease; however, the mechanisms by which microglia are …