[HTML][HTML] Towards personalized treatment of prostate cancer: PSMA I&T, a promising prostate-specific membrane antigen-targeted theranostic agent

KLS Chatalic, S Heskamp, M Konijnenberg… - Theranostics, 2016 - ncbi.nlm.nih.gov
Prostate-specific membrane antigen (PSMA) is a well-established target for nuclear imaging
and therapy of prostate cancer (PCa). Radiolabeled small-molecule PSMA inhibitors are …

PSMA-targeting imaging and theranostic agents—Current status and future perspective

S Debnath, N Zhou, M McLaughlin, S Rice… - International journal of …, 2022 - mdpi.com
In the past two decades, extensive efforts have been made to develop agents targeting
prostate-specific membrane antigen (PSMA) for prostate cancer imaging and therapy. To …

More than meets the eye: scientific rationale behind molecular imaging and therapeutic targeting of prostate-specific membrane antigen (PSMA) in metastatic prostate …

A Hyväkkä, V Virtanen, J Kemppainen, TJ Grönroos… - Cancers, 2021 - mdpi.com
Simple Summary Prostate-specific membrane antigen (PSMA) is a transmembrane protein
that is overexpressed in prostate cancer and correlates with the aggressiveness of the …

Recent developments of prostate-specific membrane antigen (PSMA)-specific radiopharmaceuticals for precise imaging and therapy of prostate cancer: an overview

SM Okarvi - Clinical and Translational Imaging, 2019 - Springer
Despite significant research activities and subsequent progress made in the fight against
cancer over the last few decades, prostate cancer remains a major health-related problem …

[HTML][HTML] Targeted α-therapy of prostate cancer using radiolabeled PSMA inhibitors: a game changer in nuclear medicine

R Chakravarty, CM Siamof, A Dash… - American journal of …, 2018 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is one of the most common malignancies in men and is a major
contributor to cancer related deaths worldwide. Metastatic spread and disease progression …

[HTML][HTML] 177Lu-labeled phosphoramidate-based PSMA inhibitors: the effect of an albumin binder on biodistribution and therapeutic efficacy in prostate tumor-bearing …

CJ Choy, X Ling, JJ Geruntho, SK Beyer, JD Latoche… - Theranostics, 2017 - ncbi.nlm.nih.gov
Prostate-specific membrane antigen (PSMA) continues to be an active biomarker for small-
molecule PSMA-targeted imaging and therapeutic agents for prostate cancer and various …

Assessment of an 18F-labeled phosphoramidate peptidomimetic as a new prostate-specific membrane antigen–targeted imaging agent for prostate cancer

SE Lapi, H Wahnishe, D Pham, LY Wu… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a transmembrane protein commonly found
on the surface of late-stage and metastatic prostate cancer and a well-known imaging …

[HTML][HTML] PSMA ligands for radionuclide imaging and therapy of prostate cancer: clinical status

S Lütje, S Heskamp, AS Cornelissen, TD Poeppel… - Theranostics, 2015 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the most common malignancy in men worldwide, leading to
substantial morbidity and mortality. At present, imaging of PCa has become increasingly …

PSMA theranostics: review of the current status of PSMA-targeted imaging and radioligand therapy

W Jones, K Griffiths, PC Barata, CJ Paller - Cancers, 2020 - mdpi.com
Prostate-specific membrane antigen (PSMA) has been the subject of extensive investigation
in the past two decades as a promising molecular target for prostate cancer (PCa). Its …

The future of PSMA-targeted radionuclide therapy: an overview of recent preclinical research

EAM Ruigrok, WM van Weerden, J Nonnekens… - Pharmaceutics, 2019 - mdpi.com
Prostate specific membrane antigen (PSMA) has become a major focus point in the research
and development of prostate cancer (PCa) imaging and therapeutic strategies using …