Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial

Z Chen, J Hu, Z Zhang, S Jiang, S Han, D Yan… - medrxiv, 2020 - medrxiv.org
Aims Studies have indicated that chloroquine (CQ) shows antagonism against COVID-19 in
vitro. However, evidence regarding its effects in patients is limited. This study aims to …

An updated systematic review of the therapeutic role of hydroxychloroquine in coronavirus disease-19 (COVID-19)

S Das, S Bhowmick, S Tiwari, S Sen - Clinical drug investigation, 2020 - Springer
Abstract Background and Objective The world is currently experiencing the Coronavirus
Disease-19 (COVID-19) pandemic. There is no approved drug for the definitive treatment of …

Effect of hydroxychloroquine in hospitalized patients with Covid-19

RECOVERY Collaborative Group - New England Journal of …, 2020 - Mass Medical Soc
Background Hydroxychloroquine and chloroquine have been proposed as treatments for
coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from …

Should chloroquine and hydroxychloroquine be used to treat COVID-19? A rapid review

K Gbinigie, K Frie - BJGP open, 2020 - bjgpopen.org
Background On the 11 March 2020, the World Health Organization (WHO) declared that
COVID-19 was a pandemic. To date, there are no medical treatments for COVID-19 with …

A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19

A Cortegiani, G Ingoglia, M Ippolito, A Giarratano… - Journal of critical …, 2020 - Elsevier
Abstract Purpose COVID-19 (coronavirus disease 2019) is a public health emergency of
international concern. As of this time, there is no known effective pharmaceutical treatment …

A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with …

CP Chen, YC Lin, TC Chen, TY Tseng, HL Wong… - PloS one, 2020 - journals.plos.org
Objective In this study, we evaluated the efficacy of hydroxychloroquine (HCQ) against
coronavirus disease 2019 (COVID-19) via a randomized controlled trial (RCT) and a …

Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19

M Huang, M Li, F Xiao, P Pang, J Liang… - National Science …, 2020 - academic.oup.com
Effective therapies are urgently needed for the SARS-CoV-2 pandemic. Chloroquine has
been proved to have antiviral effect against coronavirus in vitro. In this study, we aimed to …

Chloroquine and hydroxychloroquine for the treatment of COVID-19: a systematic review and meta-analysis

A Elavarasi, M Prasad, T Seth, RK Sahoo… - Journal of general …, 2020 - Springer
Background There is no effective therapy for COVID-19. Hydroxychloroquine (HCQ) and
chloroquine (CQ) have been used for its treatment but their safety and efficacy remain …

Treating COVID-19 with hydroxychloroquine (TEACH): a multicenter, double-blind randomized controlled trial in hospitalized patients

RJ Ulrich, AB Troxel, E Carmody… - Open forum …, 2020 - academic.oup.com
Background Effective therapies to combat coronavirus 2019 (COVID-19) are urgently
needed. Hydroxychloroquine (HCQ) has in vitro antiviral activity against severe acute …

[HTML][HTML] Hydroxychloroquine in the treatment of COVID-19: a multicenter randomized controlled study

S Abd-Elsalam, ES Esmail, M Khalaf… - The American journal …, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic is showing an exponential growth, mandating an urgent need to
develop an effective treatment. Indeed, to date, a well-established therapy is still lacking. We …