Epigenetic integration of the developing brain and face

TE Parsons, EJ Schmidt, JC Boughner… - Developmental …, 2011 - Wiley Online Library
The integration of the brain and face and to what extent this relationship constrains or
enables evolutionary change in the craniofacial complex is an issue of long‐standing …

[HTML][HTML] Molecular interactions coordinating the development of the forebrain and face

RS Marcucio, DR Cordero, D Hu, JA Helms - Developmental biology, 2005 - Elsevier
From an architectural point of view, the forebrain acts as a framework upon which the middle
and upper face develops and grows. In addition to serving a structural role, we present …

Normative brain size variation and brain shape diversity in humans

PK Reardon, J Seidlitz, S Vandekar, S Liu, R Patel… - Science, 2018 - science.org
Brain size variation over primate evolution and human development is associated with shifts
in the proportions of different brain regions. Individual brain size can vary almost twofold …

[HTML][HTML] Genome-wide association studies of brain imaging phenotypes in UK Biobank

LT Elliott, K Sharp, F Alfaro-Almagro, S Shi, KL Miller… - Nature, 2018 - nature.com
The genetic architecture of brain structure and function is largely unknown. To investigate
this, we carried out genome-wide association studies of 3,144 functional and structural brain …

Short‐faced mice and developmental interactions between the brain and the face

JC Boughner, S Wat, VM Diewert, NM Young… - Journal of …, 2008 - Wiley Online Library
The length of the face represents an important axis of variation in mammals and especially
in primates. Mice with mutations that produce variation along this axis present an opportunity …

[HTML][HTML] Genome-wide association study of facial morphology reveals novel associations with FREM1 and PARK2

MK Lee, JR Shaffer, EJ Leslie, E Orlova, JC Carlson… - PloS one, 2017 - journals.plos.org
Several studies have now shown evidence of association between common genetic variants
and quantitative facial traits in humans. The reported associations generally involve simple …

[HTML][HTML] Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

E Hofer, GV Roshchupkin, HHH Adams, MJ Knol… - Nature …, 2020 - nature.com
Cortical thickness, surface area and volumes vary with age and cognitive function, and in
neurological and psychiatric diseases. Here we report heritability, genetic correlations and …

[HTML][HTML] Morphological and population genomic evidence that human faces have evolved to signal individual identity

MJ Sheehan, MW Nachman - Nature communications, 2014 - nature.com
Facial recognition plays a key role in human interactions, and there has been great interest
in understanding the evolution of human abilities for individual recognition and tracking …

Face–brain asymmetry in autism spectrum disorders

P Hammond, C Forster-Gibson, AE Chudley… - Molecular …, 2008 - nature.com
The heterogeneity of autism spectrum disorders (ASDs) confounds attempts to identify
causes and pathogenesis. Identifiable endophenotypes and reliable biomarkers within …

Transcriptional landscape of the prenatal human brain

JA Miller, SL Ding, SM Sunkin, KA Smith, L Ng… - Nature, 2014 - nature.com
The anatomical and functional architecture of the human brain is mainly determined by
prenatal transcriptional processes. We describe an anatomically comprehensive atlas of the …