Inflammatory bowel disease as a model for translating the microbiome

C Huttenhower, AD Kostic, RJ Xavier - Immunity, 2014 - cell.com
The inflammatory bowel diseases (IBDs) are among the most closely studied chronic
inflammatory disorders that involve environmental, host genetic, and commensal microbial …

The gut microbiome and inflammatory bowel diseases

Y Shan, M Lee, EB Chang - Annual review of medicine, 2022 - annualreviews.org
Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …

The gut microbiota and inflammatory bowel diseases

J Miyoshi, EB Chang - Translational Research, 2017 - Elsevier
Inflammatory bowel diseases (IBDs) are chronic diseases of unclear etiology that affect over
1 million individuals in the United States and over 2.5 million people in Europe. However …

The microbiome in inflammatory bowel disease: current status and the future ahead

AD Kostic, RJ Xavier, D Gevers - Gastroenterology, 2014 - Elsevier
Studies of the roles of microbial communities in the development of inflammatory bowel
disease (IBD) have reached an important milestone. A decade of genome-wide association …

Inflammatory bowel diseases (IBD) and the microbiome—searching the crime scene for clues

M Lee, EB Chang - Gastroenterology, 2021 - Elsevier
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial,
immunological, and genetic factors. Alterations in the gut microbiota have been associated …

The intestinal microbiota in the pathogenesis of inflammatory bowel diseases: new insights into complex disease

KG Harris, EB Chang - Clinical Science, 2018 - portlandpress.com
Inflammatory bowel diseases (IBD) are a group of chronic diseases of increasing worldwide
prevalence characterized by gastrointestinal (GI) inflammation leading to debilitating …

Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …

Functional impacts of the intestinal microbiome in the pathogenesis of inflammatory bowel disease

J Li, J Butcher, D Mack, A Stintzi - Inflammatory bowel diseases, 2015 - academic.oup.com
The human intestinal microbiome plays a critical role in human health and disease,
including the pathogenesis of inflammatory bowel disease (IBD). Numerous studies have …

The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …

[PDF][PDF] Host-microbial cross-talk in inflammatory bowel disease

H Nagao-Kitamoto, N Kamada - Immune network, 2017 - synapse.koreamed.org
A vast community of commensal microorganisms, commonly referred to as the gut
microbiota, colonizes the gastrointestinal tract (GI). The involvement of the gut microbiota in …