Current and future treatment landscape for idiopathic pulmonary fibrosis

F Bonella, P Spagnolo, C Ryerson - Drugs, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) remains a disease with poor survival. The pathogenesis
is complex and encompasses multiple molecular pathways. The first-generation antifibrotics …

Pharmacological treatment of idiopathic pulmonary fibrosis: current approaches, unsolved issues, and future perspectives

M Kreuter, F Bonella, M Wijsenbeek… - BioMed research …, 2015 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a devastating condition with a 5‐year survival of
approximately 20%. The disease primarily occurs in elderly patients. IPF is a highly …

Idiopathic pulmonary fibrosis: Disease mechanisms and drug development

P Spagnolo, JA Kropski, MG Jones, JS Lee… - Pharmacology & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …

[HTML][HTML] Idiopathic pulmonary fibrosis

T Koudstaal, MS Wijsenbeek - La Presse Médicale, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive devastating lung disease with substantial
morbidity. It is associated with cough, dyspnea and impaired quality of life. If left untreated …

Novel drug targets for idiopathic pulmonary fibrosis

G Sgalla, E Cocconcelli, R Tonelli… - Expert review of …, 2016 - Taylor & Francis
ABSTRACT Idiopathic Pulmonary Fibrosis (IPF) is a progressive, fatal lung disorder of
unknown cause with a highly variable and unpredictable clinical course. The advances …

The therapy of idiopathic pulmonary fibrosis: what is next?

V Somogyi, N Chaudhuri, SE Torrisi… - European …, 2019 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease, characterised by progressive scarring of the lung and associated with a high …

Pharmacological management of IPF

R Borie, A Justet, G Beltramo, ED Manali… - …, 2016 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a deadly disease with a median survival of
approximately three years in historical cohorts. Despite increased knowledge of disease …

Update on therapeutic management of idiopathic pulmonary fibrosis

A Tzouvelekis, F Bonella… - Therapeutics and clinical …, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive diffuse parenchymal lung
disease of unknown origin, with a mortality rate exceeding that of many cancers. The …

Targeted therapy for idiopathic pulmonary fibrosis: where to now?

S Rangarajan, ML Locy, TR Luckhardt, VJ Thannickal - Drugs, 2016 - Springer
Idiopathic pulmonary fibrosis (IPF) is an aging-associated, recalcitrant lung disease with
historically limited therapeutic options. The recent approval of two drugs, pirfenidone and …

Idiopathic pulmonary fibrosis: the turning point is now!

M Funke, T Geiser - Swiss medical weekly, 2015 - smw.ch
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with poor survival.
Recent studies have improved understanding of IPF and new discoveries have led to novel …