Macrophages have been suggested to be beneficial for myocardial wound healing. We
investigated the role of macrophages in myocardial wound healing by inhibition of …

The immune system plays a pivotal role in the initiation, development and resolution of
inflammation following insult or damage to organs. The heart is a vital organ which supplies …

Alternatively activated (also known as M2) macrophages are involved in the repair of various
types of organs. However, the contribution of M2 macrophages to cardiac repair after …

Background—Activated macrophages have a significant role in wound healing and
damaged tissue repair. We sought to explore the ability of ex vivo activated macrophages to …

Following myocardial infarction (MI), circulating blood monocytes respond to chemotactic
factors, migrate into the infarcted myocardium, and differentiate into macrophages. At the …

Fibrosis induced by prolonged inflammation is a major pathophysiological feature of
adverse left ventricular remodeling after myocardial infarction and pathological cardiac …

Myocardial infarction (MI) leads to rapid necrosis of cardiac myocytes. To achieve tissue
integrity and function, inflammatory cells are activated, including monocytes/macrophages …

Myocardial infarction is the most common form of acute cardiac injury attributing to heart
failure. While there have been significant advances in current therapies, mortality and …

Rationale: Macrophages reside in the healthy myocardium, participate in ischemic heart
disease, and modulate myocardial infarction (MI) healing. Their origin and roles in post-MI …

Ischemic heart disease is a growing worldwide epidemic. Improvements in medical and
surgical therapies have reduced early mortality after acute myocardial infarction and …