The redox chemistry of copper (Cu) makes this both a powerful enzyme catalyst and a
dangerous reactant that generates hydroxyl radical. Although virtually all cells from microbes …

Copper is an essential nutrient that serves as a co-factor for enzymes involved in critical
cellular processes including energy generation, peptide hormone maturation, oxidative …

The redox active metal copper is an essential cofactor in critical biological processes such
as respiration, iron transport, oxidative stress protection, hormone production, and …

The trace metal copper (Cu) plays an essential role in biology as a cofactor for many
enzymes that include Cu, Zn superoxide dismutase, cytochrome oxidase, ceruloplasmin …

Copper plays an essential role in human physiology. It is required for respiration, radical
defense, neuronal myelination, angiogenesis, and many other processes. Copper has …

A polymerase chain reaction (PCR)-based strategy was used to isolate a mouse cDNA
(mCtr1) encoding a Cu transport protein. The deduced mCtr1 protein sequence exhibits …

Copper is an essential nutrient required for the activity of a number of enzymes with diverse
biological roles. In the bakers' yeast Saccharomyces cerevisiae, copper is transported into …

The trace metal copper is an essential cofactor for a number of biological processes
including mitochondrial oxidative phosphorylation, free radical detoxification …

In the past few years, exciting advances have been made toward understanding how copper
is transported into and distributed to cupro-proteins within cells. Recent work has identified …

The cellular uptake and intracellular distribution of the essential but highly toxic nutrient,
copper, is a precisely orchestrated process. Copper homeostasis is coordinated by several …