The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies

C Chen, X ZHANG, Z JU, W HE - Chinese journal of burns, 2020 - pesquisa.bvsalud.org
ABSTRACT Corona Virus Disease 2019 (COVID-19) has seriously affected the treatment of
patients and social stability. In the later stage of disease, some COVID-19 patients may …

The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …

[HTML][HTML] Hazards of the cytokine storm and cytokine-targeted therapy in patients with COVID-19

M Quirch, J Lee, S Rehman - Journal of medical Internet research, 2020 - jmir.org
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
challenged medicine and health care on a global scale. Its impact and frightening mortality …

[HTML][HTML] The role of Interleukin 6 inhibitors in therapy of severe COVID-19

E Nasonov, M Samsonov - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cytokine storm syndrome (CSS) is a severe complication of inflammatory immune diseases
or treatment of malignancies; it may also appear during the progression of COVID-19. CSS …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) infection, has emerged in China in December 2019 …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
Corona Virus Disease 2019 (COVID-19) pandemic is rapidly spreading all over the world.
Excessive immune responses trigger life-threatening cytokine release syndrome (CRS) …