[HTML][HTML] When does the cytokine storm begin in COVID-19 patients? A quick score to recognize it

S Cappanera, M Palumbo, SH Kwan, G Priante… - Journal of clinical …, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that is
responsible for coronavirus disease 2019 (COVID-19), which has rapidly spread across the …

[HTML][HTML] Sepsis-associated severe interleukin-6 storm in critical coronavirus disease 2019

L Huang, X Zhao, Y Qi, H Li, G Ye, Y Liu… - Cellular & molecular …, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by a novel
coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 1, 2 …

[HTML][HTML] Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
Objective To describe the laboratory parameters and biomarkers of the cytokine storm
syndrome associated with severe and fatal COVID-19 cases. Methods A search with …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

[HTML][HTML] Cytokine storm and immunomodulatory therapy in COVID-19: role of chloroquine and anti-IL-6 monoclonal antibodies

M Zhao - International journal of antimicrobial agents, 2020 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus-2, the causative agent of coronavirus
disease 2019 (COVID-19), was declared a pandemic by the World Health Organization on …

[PDF][PDF] Cytokine-targeted therapy in severely ill COVID-19 patients: options and cautions

M Rahmati, MA Moosavi - mortality, 2020 - researchgate.net
Dear Editor, Coronavirus disease 2019 (COVID-19) is an infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) with the symptoms …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

Clinical outcomes in COVID‐19 patients treated with tocilizumab: an individual patient data systematic review

D Antwi‐Amoabeng, Z Kanji, B Ford… - Journal of medical …, 2020 - Wiley Online Library
Background Current evidence suggests an important role of the interleukin‐6 (IL‐6) pathway
in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐related cytokine …

[HTML][HTML] Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy

Y Jiang, L Rubin, T Peng, L Liu, X Xing… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
The COVID-19 outbreak is emerging as a significant public health challenge. Excessive
production of proinflammatory cytokines, also known as cytokine storm, is a severe clinical …

COVID‐19: Consider IL‐6 receptor antagonist for the therapy of cytokine storm syndrome in SARS‐CoV‐2 infected patients

C Chakraborty, AR Sharma… - Journal of medical …, 2020 - Wiley Online Library
COVID‐19 leads to mortality of several patients and the cytokine storm is reportedly critical
in the patients. To reduce the cytokine storm, we would like to propose the interleukin (IL) 6 …