Background Osteosarcoma is a disease with high mortality in children and adolescents, and
metastasis is one of the important clinical features of osteosarcoma. N 6-Methyladenosine …

Background: Osteosarcoma represents the most common malignant bone tumor with high
metastatic potential and inferior prognosis. RNA methylation (N6-methyladenosine [m6A]) is …

Background: Osteosarcoma (OS) is the most common primary bone tumor. The disease has
a poor prognosis due to the delay in the diagnosis and the development of metastasis. N6 …

Osteosarcoma (OS) is characterized by rapid growth and early metastasis. However, its
mechanism remains unclear. N 6-methyladenosine (m 6 A) modification and its regulatory …

Osteosarcoma (OS) is the most common primary malignant bone tumor in children and
young adults and has a poor prognosis. Recent developments in the field of high-throughput …

Osteosarcoma is the most common primary bone malignancy, typically occurring in
childhood or adolescence. Unfortunately, the clinical outcomes of patients with …

Aim: To analyze the m6A methylome of osteosarcoma stem cells (OSCs). Materials &
methods: Chemoresistant OSCs were enriched by doxorubicin treatment. Expression of m6A …

Background. Osteosarcoma is a common and highly metastatic malignant tumor, and m5C
RNA methylation regulates various biological processes. The purpose of this study was to …

N6-Adenosine methylation, yielding N6-methyladenosine (m6A), is a reversible epigenetic
modification found in messenger RNAs and long non-coding RNAs (lncRNAs), which affects …

Osteosarcoma (OS) is the most common and aggressive malignant bone sarcoma, which
occurs in rapidly growing bones in children and adolescents. However, the underlying …