Evaluation of post-introduction COVID-19 vaccine effectiveness: Summary of interim guidance of the World Health Organization

MK Patel, I Bergeri, JS Bresee, BJ Cowling… - Vaccine, 2021 - Elsevier
Phase 3 randomized-controlled trials have provided promising results of COVID-19 vaccine
efficacy, ranging from 50 to 95% against symptomatic disease as the primary endpoints …

Are some COVID-19 vaccines better than others? Interpreting and comparing estimates of efficacy in vaccine trials

RR Rapaka, EA Hammershaimb… - Clinical Infectious …, 2022 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) vaccine trials provide valuable insight into
the safety and efficacy of vaccines, with individually randomized, placebo-controlled trials …

[HTML][HTML] Evaluation of the safety profile of COVID-19 vaccines: a rapid review

Q Wu, MZ Dudley, X Chen, X Bai, K Dong, T Zhuang… - BMC medicine, 2021 - Springer
Background The rapid process of research and development and lack of follow-up time post-
vaccination aroused great public concern about the safety profile of COVID-19 vaccine …

A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease

MM Higdon, B Wahl, CB Jones, JG Rosen, SA Truelove… - MedRXiv, 2021 - medrxiv.org
Billions of doses of COVID-19 vaccines have been administered globally, dramatically
reducing SARS-CoV-2 incidence and severity in some settings. Many studies suggest …

[HTML][HTML] Efficacy and safety of COVID-19 vaccines in phase III trials: a meta-analysis

H Cheng, Z Peng, W Luo, S Si, M Mo, H Zhou, X Xin… - Vaccines, 2021 - mdpi.com
Nowadays, the vaccination with COVID-19 vaccines is being promoted worldwide,
professionals and common people are very concerned about the efficacy and safety of …

[HTML][HTML] Duration of effectiveness of vaccines against SARS-CoV-2 infection and COVID-19 disease: results of a systematic review and meta-regression

DR Feikin, MM Higdon, LJ Abu-Raddad, N Andrews… - The lancet, 2022 - thelancet.com
Background Knowing whether COVID-19 vaccine effectiveness wanes is crucial for
informing vaccine policy, such as the need for and timing of booster doses. We aimed to …

[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2

SH Hodgson, K Mansatta, G Mallett, V Harris… - The lancet infectious …, 2021 - thelancet.com
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …

Ongoing and future COVID-19 vaccine clinical trials: challenges and opportunities

R Dal-Ré, LG Bekker, C Gluud, S Holm… - The Lancet Infectious …, 2021 - thelancet.com
Large-scale deployment of COVID-19 vaccines will seriously affect the ongoing phases 2
and 3 randomised placebo-controlled trials assessing SARS-CoV-2 vaccine candidates …

[HTML][HTML] Effectiveness of an inactivated SARS-CoV-2 vaccine

A Wilder-Smith, K Mulholland - New England Journal of Medicine, 2021 - Mass Medical Soc
The world needs more vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), in order to …

Prospects for a safe COVID-19 vaccine

BF Haynes, L Corey, P Fernandes, PB Gilbert… - Science translational …, 2020 - science.org
Rapid development of an efficacious vaccine against the viral pathogen severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of the coronavirus disease …