Glutamate at the site of phosphorylation of nitrogen-regulatory protein NTRC mimics aspartyl-phosphate and activates the protein
The NTRC protein of enteric bacteria is an enhancer-binding protein that activates
transcription by the σ 54-holoenzyme form of RNA polymerase under nitrogen-limiting …
transcription by the σ 54-holoenzyme form of RNA polymerase under nitrogen-limiting …
The major dimerization determinants of the nitrogen regulatory protein NTRC from enteric bacteria lie in its carboxy-terminal domain
KE Klose, AK North, KM Stedman, S Kustu - Journal of molecular biology, 1994 - Elsevier
The NTRC protein (nitrogen regulatory protein C) of enteric bacteria is an enhancer-binding
protein that activates transcription by the σ 54-holoenzyme form of RNA polymerase. NTRC …
protein that activates transcription by the σ 54-holoenzyme form of RNA polymerase. NTRC …
The phosphorylated form of the enhancer-binding protein NTRC has an ATPase activity that is essential for activation of transcription
The NTRC protein of enteric bacteria is an enhancerbinding protein that activates
transcription in response to limitation of combined nitrogen. NTRC activates transcription by …
transcription in response to limitation of combined nitrogen. NTRC activates transcription by …
Protein kinase and phosphoprotein phosphatase activities of nitrogen regulatory proteins NTRB and NTRC of enteric bacteria: roles of the conserved amino-terminal …
J Keener, S Kustu - … of the National Academy of Sciences, 1988 - National Acad Sciences
The NTRC protein (ntrC product) of enteric bacteria activates transcription of nitrogen-
regulated genes by a holoenzyme form of RNA polymerase that contains the ntrA product …
regulated genes by a holoenzyme form of RNA polymerase that contains the ntrA product …
Repressor forms of the enhancer-binding protein NtrC: some fail in coupling ATP hydrolysis to open complex formation by σ54-holoenzyme
AK North, DS Weiss, H Suzuki, Y Flashner… - Journal of molecular …, 1996 - Elsevier
NtrC (nitrogen regulatory protein C) is a bacterial enhancer-binding protein that activates
transcription by catalyzing isomerization of closed complexes between σ54-holoenzyme and …
transcription by catalyzing isomerization of closed complexes between σ54-holoenzyme and …
Constitutive forms of the enhancer-binding protein NtrC: evidence that essential oligomerization determinants lie in the central activation domain
Y Flashner, DS Weiss, J Keener, S Kustu - Journal of molecular biology, 1995 - Elsevier
Nitrogen regulatory protein C (NtrC) is a bacterial enhancer-binding protein that activates
transcription by the σ54-holoenzyme. To activate transcription, NtrC must hydrolyze ATP, a …
transcription by the σ54-holoenzyme. To activate transcription, NtrC must hydrolyze ATP, a …
Mechanism of transcriptional activation by NtrC
SC Porter, AK North, S Kustu - Two‐Component Signal …, 1995 - Wiley Online Library
In the case of nitrogen regulatory protein C (NtrC), both nucleotide hydrolysis and
transcriptional activation depend on phosphorylation of an aspartate residue in the N …
transcriptional activation depend on phosphorylation of an aspartate residue in the N …
Phosphorylation site of NtrC, a protein phosphatase whose covalent intermediate activates transcription
DA Sanders, BL Gillece-Castro… - Journal of …, 1992 - Am Soc Microbiol
The NtrC transcription factor is a member of a family of homologous prokaryotic regulatory
proteins that participate in the transduction of extracellular and nutritional signals. It has …
proteins that participate in the transduction of extracellular and nutritional signals. It has …
MgATP binding and hydrolysis determinants of NtrC, a bacterial enhancer-binding protein
I Rombel, P Peters-Wendisch, A Mesecar… - Journal of …, 1999 - Am Soc Microbiol
When phosphorylated, the dimeric form of nitrogen regulatory protein C (NtrC) of Salmonella
typhimurium forms a larger oligomer (s) that can hydrolyze ATP and hence activate …
typhimurium forms a larger oligomer (s) that can hydrolyze ATP and hence activate …
Influence of a mutation in the putative nucleotide binding site of the nitrogen regulatory protein NTRC on its positive control function
S Austin, C Kundrot, R Dixon - Nucleic acids research, 1991 - academic.oup.com
A mutation, serine 170 to alanine, in the proposed ATP binding site of the activator protein
NTRC prevents transcriptional activation at σ 54-dependent promoters both in vivo and in …
NTRC prevents transcriptional activation at σ 54-dependent promoters both in vivo and in …