Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …

The pathogenesis of pandemic coronavirus disease-2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely depends heavily on …

Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …

Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

The exaggerated immune response induced in the lower respiratory tract against
coronaviruses (CoVs), including CoViD-19 (2019-nCoV), appears to contribute to the …