Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing major threat to global …

COVID-19: towards understanding of pathogenesis

W Cao, T Li - Cell research, 2020 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) is spreading rapidly. Although the
cause was quickly identified as a new coronavirus named SARS-CoV-2, our knowledge of …

Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes
coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has …

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

L Vanderbeke, P Van Mol, Y Van Herck… - Nature …, 2021 - nature.com
Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the
triggering of an aberrant host immune response, more so than on direct virus-induced …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …

Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome

D Weiskopf, KS Schmitz, MP Raadsen, A Grifoni… - Science …, 2020 - science.org
SARS-CoV-2 has been identified as the causative agent of a global outbreak of respiratory
tract disease (COVID-19). In some patients, the infection results in moderate to severe acute …

Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …