Tissue-specific immunopathology in fatal COVID-19
Rationale: In life-threatening coronavirus disease (COVID-19), corticosteroids reduce
mortality, suggesting that immune responses have a causal role in death. Whether this …
mortality, suggesting that immune responses have a causal role in death. Whether this …
Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection
The outbreak of coronavirus disease 2019 (COVID‐19) and pandemic, caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has become a major concern …
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has become a major concern …
Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients
C Wang, J Xie, L Zhao, X Fei, H Zhang, Y Tan, X Nie… - …, 2020 - thelancet.com
Background The novel coronavirus pneumonia COVID-19 caused by SARS-CoV-2 infection
could lead to a series of clinical symptoms and severe illnesses, including acute respiratory …
could lead to a series of clinical symptoms and severe illnesses, including acute respiratory …
Hyperinflammatory response in COVID-19: a systematic review
MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …
to acute respiratory distress syndrome and death. Three highly pathogenic human …
The deregulated immune reaction and cytokines release storm (CRS) in COVID-19 disease
R Pasrija, M Naime - International Immunopharmacology, 2021 - Elsevier
COVID-19 caused by the SARS-CoV-2 virus, accompanies an unprecedented spike in
cytokines levels termed cytokines release syndrome (CRS), in critically ill patients. Clinicians …
cytokines levels termed cytokines release syndrome (CRS), in critically ill patients. Clinicians …
Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents
Abstract Background Coronavirus disease 2019 (COVID-19) is caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel …
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel …
Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19
Many studies have been performed in severe COVID-19 on immune cells in the circulation
and on cells obtained by bronchoalveolar lavage. Most studies have tended to provide …
and on cells obtained by bronchoalveolar lavage. Most studies have tended to provide …
Why tocilizumab could be an effective treatment for severe COVID-19?
B Fu, X Xu, H Wei - Journal of translational medicine, 2020 - Springer
A severe pneumonia-associated respiratory syndrome caused by a new coronavirus was
identified in December 2019 (COVID-19), spread rapidly and has become a world-wide …
identified in December 2019 (COVID-19), spread rapidly and has become a world-wide …
Novel coronavirus disease 2019 (COVID-19) and cytokine storms for more effective treatments from an inflammatory pathophysiology
S Yokota, T Miyamae, Y Kuroiwa… - Journal of Clinical …, 2021 - mdpi.com
The Novel Coronavirus Disease 2019 (COVID-19) has swept the world and caused a global
pandemic. SARS-CoV-2 seems to have originated from bats as their reservoir hosts over …
pandemic. SARS-CoV-2 seems to have originated from bats as their reservoir hosts over …