[HTML][HTML] m7GHub V2.0: an updated database for decoding the N7-methylguanosine (m7G) epitranscriptome

X Wang, Y Zhang, K Chen, Z Liang, J Ma… - Nucleic Acids …, 2024 - academic.oup.com
With recent progress in mapping N7-methylguanosine (m7G) RNA methylation sites, tens of
thousands of experimentally validated m7G sites have been discovered in various species …

m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human

B Song, Y Tang, K Chen, Z Wei, R Rong, Z Lu… - …, 2020 - academic.oup.com
Motivation Recent progress in N7-methylguanosine (m7G) RNA methylation studies has
focused on its internal (rather than capped) presence within mRNAs. Tens of thousands of …

[HTML][HTML] Internal m7G methylation: a novel epitranscriptomic contributor in brain development and diseases

X Xia, Y Wang, JC Zheng - Molecular Therapy-Nucleic Acids, 2023 - cell.com
In recent years, N7-methylguanosine (m7G) methylation, originally considered as
messenger RNA (mRNA) 5′ caps modifications, has been identified at defined internal …

[HTML][HTML] Transcriptome-wide mapping of internal N7-methylguanosine methylome in mammalian mRNA

LS Zhang, C Liu, H Ma, Q Dai, HL Sun, G Luo, Z Zhang… - Molecular cell, 2019 - cell.com
Summary N 7-methylguanosine (m 7 G) is a positively charged, essential modification at the
5′ cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m 7 G also …

Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing

C Enroth, LD Poulsen, S Iversen, F Kirpekar… - Nucleic acids …, 2019 - academic.oup.com
Methylation of guanosine on position N7 (m7G) on internal RNA positions has been found in
all domains of life and have been implicated in human disease. Here, we present m7G …

Dynamic methylome of internal mRNA N7-methylguanosine and its regulatory role in translation

L Malbec, T Zhang, YS Chen, Y Zhang, BF Sun, BY Shi… - Cell research, 2019 - nature.com
Over 150 types of RNA modifications are identified in RNA molecules. Transcriptome
profiling is one of the key steps in decoding the epitranscriptomic panorama of these …

When N7-methyladenosine modification meets cancer: Emerging frontiers and promising therapeutic opportunities

D Du, J He, C Ju, C Wang, H Li, F He, M Zhou - Cancer Letters, 2023 - Elsevier
Abstract N 7-methylguanosine (m 7 G) methylation, one of the most common RNA
modifications in eukaryotes, has recently gained considerable attention. The biological …

m6A-TSHub: Unveiling the Context-Specific m6A Methylation and m6A-Affecting Mutations in 23 Human Tissues

B Song, D Huang, Y Zhang, Z Wei, J Su… - Genomics …, 2023 - academic.oup.com
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …

m7G-quant-seq: Quantitative Detection of RNA Internal N7-Methylguanosine

LS Zhang, CW Ju, C Liu, J Wei, Q Dai… - ACS Chemical …, 2022 - ACS Publications
Methods for the precise detection and quantification of RNA modifications are critical to
uncover functional roles of diverse RNA modifications. The internal m7G modification in …

Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI

C Liu, H Sun, Y Yi, W Shen, K Li, Y Xiao, F Li, Y Li… - Nature …, 2023 - nature.com
Abstract N 6-methyladenosine (m6A) is the most abundant RNA modification in mammalian
cells and the best-studied epitranscriptomic mark. Despite the development of various tools …